Browsing by Subject "GESTATIONAL-AGE"

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Now showing items 21-23 of 23
  • Heinonen, Kati; Räikkönen, Katri; Pesonen, Anu-Katriina; Andersson, Sture; Kajantie, Eero; Eriksson, Johan G.; Vartia, Timo; Wolke, Dieter; Lano, Aulikki (2011)
  • Yokoyama, Yoshie; Jelenkovic, Aline; Sund, Reijo; Sung, Joohon; Hopper, John L.; Ooki, Syuichi; Heikkila, Kauko; Aaltonen, Sari; Tarnoki, Adam D.; Tarnoki, David L.; Willemsen, Gonneke; Bartels, Meike; van Beijsterveldt, Toos C. E. M.; Saudino, Kimberly J.; Cutler, Tessa L.; Nelson, Tracy L.; Whitfield, Keith E.; Wardle, Jane; Llewellyn, Clare H.; Fisher, Abigail; He, Mingguang; Ding, Xiaohu; Bjerregaard-Andersen, Morten; Beck-Nielsen, Henning; Sodemann, Morten; Song, Yun-Mi; Yang, Sarah; Lee, Kayoung; Jeong, Hoe-Uk; Knafo-Noam, Ariel; Mankuta, David; Abramson, Lior; Burt, S. Alexandra; Klump, Kelly L.; Ordonana, Juan R.; Sanhez-Romera, Juan F.; Colodro-Conde, Lucia; Harris, Jennifer R.; Brandt, Ingunn; Nilsen, Thomas Sevenius; Craig, Jeffrey M.; Saffery, Richard; Ji, Fuling; Ning, Feng; Pang, Zengchang; Dubois, Lise; Boivin, Michel; Brendgen, Mara; Dionne, Ginette; Vitaro, Frank; Martin, Nicholas G.; Medland, Sarah E.; Montgomery, Grant W.; Magnusson, Patrik K. E.; Pedersen, Nancy L.; Aslan, Anna K. Dahl; Tynelius, Per; Haworth, Claire M. A.; Plomin, Robert; Rebato, Esther; Rose, Richard J.; Goldberg, Jack H.; Rasmussen, Finn; Hur, Yoon-Mi; Sorensen, Thorkild I. A.; Boomsma, Dorret I.; Kaprio, Jaakko; Silventoinen, Karri (2016)
    We analyzed birth order differences in means and variances of height and body mass index (BMI) in monozygotic (MZ) and dizygotic (DZ) twins from infancy to old age. The data were derived from the international CODATwins database. The total number of height and BMI measures from 0.5 to 79.5 years of age was 397,466. As expected, first-born twins had greater birth weight than second-born twins. With respect to height, first-born twins were slightly taller than second-born twins in childhood. After adjusting the results for birth weight, the birth order differences decreased and were no longer statistically significant. First-born twins had greater BMI than the second-born twins over childhood and adolescence. After adjusting the results for birth weight, birth order was still associated with BMI until 12 years of age. No interaction effect between birth order and zygosity was found. Only limited evidence was found that birth order influenced variances of height or BMI. The results were similar among boys and girls and also in MZ and DZ twins. Overall, the differences in height and BMI between first-and second-born twins were modest even in early childhood, while adjustment for birth weight reduced the birth order differences but did not remove them for BMI.
  • 23me Res Team (2018)
    Preterm birth is a leading cause of morbidity and mortality in infants. Genetic and environmental factors play a role in the susceptibility to preterm birth, but despite many investigations, the genetic basis for preterm birth remain largely unknown. Our objective was to identify rare, possibly damaging, nucleotide variants in mothers from families with recurrent spontaneous preterm births (SPTB). DNA samples from 17 Finnish mothers who delivered at least one infant preterm were subjected to whole exome sequencing. All mothers were of northern Finnish origin and were from seven multiplex families. Additional replication samples of European origin consisted of 93 Danish sister pairs (and two sister triads), all with a history of a preterm delivery. Rare exonic variants (frequency