Browsing by Subject "moisture damage"

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  • Täubel, Martin; Karvonen, Anna M.; Reponen, Tiina; Hyvärinen, Anne; Vesper, Stephen; Pekkanen, Juha (2016)
    The environmental relative moldiness index (ERMI) metric was previously developed to quantify mold contamination in U.S. homes. This study determined the applicability of the ERMI for quantifying mold and moisture damage in Finnish residences. Homes of the LUKAS2 birth cohort in Finland were visually inspected for moisture damage and mold, and vacuumed floor dust samples were collected. An ERMI analysis including 36 mold-specific quantitative PCR assays was performed on the dust samples (n = 144), and the ERMI metric was analyzed against inspection-based observations of moisture damage and mold. Our results show that the ERMI was significantly associated with certain observations of visible mold in Finnish homes but not with moisture damage. Several mold species occurred more frequently and at higher levels in Finnish than in U.S. homes. Modification of the ERMI toward Finnish conditions, using a subsample of LUKAS2 homes with and without moisture damage, resulted in a simplified metric based on 10 mold species. The Finnish ERMI (FERMI) performed substantially better in quantifying moisture and mold damage in Finnish homes, showing significant associations with various observations of visible mold, strongest when the damage was located in the child's main living area, as well as with mold odor and moisture damage. As shown in Finland, the ERMI as such is not equally well usable in different climates and geographic regions but may be remodeled to account for local outdoor and indoor fungal conditions as well as for moisture damage characteristics in a given country.
  • Tischer, Christina; Karvonen, Anne M.; Kirjavainen, Pirkka V.; Flexeder, Claudia; Roponen, Marjut; Hyvarinen, Anne; Renz, Harald; Frey, Urs Peter; Fuchs, Oliver; Pekkanen, Juha (2021)
    Background Exposure to indoor moisture damage and visible mold has been found to be associated with asthma and respiratory symptoms in several questionnaire-based studies by self-report. We aimed to define the prospective association between the early life exposure to residential moisture damage or mold and fractional exhaled nitric oxide (FeNO) and lung function parameters as objective markers for airway inflammation and asthma in 6-year-old children. Methods Home inspections were performed in children's homes when infants were on average 5 months old. At age 6 years, data on FeNO (n = 322) as well as lung function (n = 216) measurements were collected. Logistic regression and generalized additive models were used for statistical analyses. Results Early age major moisture damage and moisture damage or mold in the child's main living areas were significantly associated with increased FeNO levels (>75th percentile) at the age of 6 years (adjusted odds ratios, 95% confidence intervals, aOR (95% CI): 3.10 (1.35-7.07) and 3.16 (1.43-6.98), respectively. Effects were more pronounced in those who did not change residential address throughout the study period. For lung function, major structural damage within the whole home was associated with reduced FEV1 and FVC, but not with FEV1/FVC. No association with lung function was observed with early moisture damage or mold in the child's main living areas. Conclusion These results underline the importance of prevention and remediation efforts of moisture and mold-damaged buildings in order to avoid harmful effects within the vulnerable phase of the infants and children's immunologic development.
  • Andersson, Maria; Salo, Johanna; Lipponen, Olli; Salonen, Pauliina; Viljanen, Martti; Ojamo, Heikki; Mikkola, Raimo; Sistonen, Esko; Gasik, Michael; Teplova, Vera V; Salin , Mikko; Salkinoja-Salonen, Mirja Sinikka (Sisäilmayhdistys, 2014)
    Raportti / Sisäilmayhdistys
    Antimikrobisia biosideja ja muita bioreaktiivisia kemikaaleja sisältyy rakennus tuotteisiin ja käytetään rakennusten ylläpidossa, huollossa, siivouksessa ja (home)saneerauksessa. Käytetyt aineet ovat pääosin pitkävaikutteisia biosideja, jotka sisätiloissa käytettyinä kertyvät muodostaen tilojen käyttäjille pysyvän kemiallisen rasitteen, koska mekanismit (luonnonvalo, sade, tuuli, biohajottavat mikrobit, jotka niitä hävittäisivät, puuttuvat. Selvitimme kokeellisesti ja kirjallisuudesta näiden kemikaalien: 1) antimikrobista tehoa terveyshaitallisiksi tunnettuihin, toksiineja tuottaviin mikrobilajeihin; 2) herkistävyyttä ja muita vaikutuksia ihmisen ja muiden lämminveristen soluihin; 3) tekijöitä, jotka vaikuttavat mikrobien haitta-aine päästöihin ja läpäisevyyteen rakennuksessa.