Browsing by Subject "Adults"

Sort by: Order: Results:

Now showing items 1-12 of 12
  • Harbach, Ralph E.; Dallimore, Thom; Briscoe, Andrew G.; Culverwell, C. Lorna; Vaux, Alexander G. C.; Medlock, Jolyon M. (2017)
    We report the discovery of Aedes nigrinus (Eckstein, 1918) in the New Forest of southern England, bringing to 36 the number of mosquito species recorded in Britain. Because it seems that this species has been misidentified previously in Britain as the morphologically similar Aedes sticticus (Meigen, 1838), the two species are contrasted and distinguished based on distinctive differences exhibited in the adult and larval stages. The pupa of Ae. nigrinus is unknown, but the pupa of Ae. sticticus is distinguished from the pupae of other species of Aedes by modification of the most recent key to British mosquitoes. The history of the mosquito fauna recorded in the UK is summarized and bionomical information is provided for the two species.
  • Piirtola, Maarit; Kaprio, Jaakko; Silventoinen, Karri; Svedberg, Pia; Korhonen, Tellervo; Ropponen, Annina (2017)
    To investigate longitudinal associations of smoking and a change in smoking status with leisure-time physical inactivity. In addition, to control whether familial confounding (genetics and shared environment) influences the associations. Data were based on the population-based Finnish Adult Twin Cohort of 5254 twin individuals born in 1945-1957 (41% men) and who participated in all four surveys over a 35-year follow-up (1975-2011). Logistic and conditional logistic regression models with multiple covariates were used for analyses. Compared to never-smokers, long-term daily smokers (1975-1990) had the highest likelihood for both long-term inactivity and to change into inactive by 2011. Recurrent smoking was associated with long-term inactivity. Instead, in comparison to persistent daily smokers, quitting smoking decreased the likelihood of becoming physically inactive at leisure time. The associations remained in the analyses which accounted for multiple covariates and/or familial confounding. Daily smoking increases the likelihood of remaining or becoming physically inactive over the decades. Our results emphasize not only the importance of preventing smoking initiation, but also to support early smoking cessation in promotion of lifelong physical activity.
  • Lallukka, Tea; Mekuria, Gashaw B.; Nummi, Tapio; Virtanen, Pekka; Virtanen, Marianna; Hammarström, Anne (2019)
    BackgroundCo-occurrence of mental and somatic symptoms is common, and recent longitudinal studies have identified single trajectories of these symptoms, but it is poorly known whether the symptom trajectories can also co-occur and change across the lifespan. We aimed to examine co-occurring symptoms and their joint trajectories from adolescence to midlife.MethodsLongitudinal data were derived from Northern Sweden, where 506 girls and 577 boys aged 16years participated at baseline in 1981 (99.7% of those initially invited), and have been followed up in four waves until the age of 43. Survey data were collected about depressive, anxiety, and somatic symptoms. Potential joint development of this three-component symptom set was examined with multiple response trajectory analysis, a method that has not been previously used to study co-occurrence of these symptoms.ResultsWe identified a five trajectory solution as the best: very low (19%), low (31%), high (22%), late sharply increasing (16%) and a very high increasing (12%). In the late sharply increasing and very high increasing groups the scores tended to increase with age, while in the other groups the levels were more stable. Overall, the results indicated that depressive, anxiety, and somatic symptoms co-exist from adolescence to midlife.ConclusionsThe multiple response trajectory analysis confirmed high stability in the co-occurrence of depressive, anxiety, and somatic symptoms from adolescence to midlife. Clinicians should consider these findings to detect symptoms in their earliest phase in order to prevent the development of co-occurring high levels of symptoms.
  • Lallukka, Tea; Mekuria, Gashaw B; Nummi, Tapio; Virtanen, Pekka; Virtanen, Marianna; Hammarström, Anne (BioMed Central, 2019)
    Abstract Background Co-occurrence of mental and somatic symptoms is common, and recent longitudinal studies have identified single trajectories of these symptoms, but it is poorly known whether the symptom trajectories can also co-occur and change across the lifespan. We aimed to examine co-occurring symptoms and their joint trajectories from adolescence to midlife. Methods Longitudinal data were derived from Northern Sweden, where 506 girls and 577 boys aged 16 years participated at baseline in 1981 (99.7% of those initially invited), and have been followed up in four waves until the age of 43. Survey data were collected about depressive, anxiety, and somatic symptoms. Potential joint development of this three-component symptom set was examined with multiple response trajectory analysis, a method that has not been previously used to study co-occurrence of these symptoms. Results We identified a five trajectory solution as the best: “very low” (19%), “low” (31%), “high” (22%), “late sharply increasing” (16%) and a “very high increasing” (12%). In the “late sharply increasing” and “very high increasing” groups the scores tended to increase with age, while in the other groups the levels were more stable. Overall, the results indicated that depressive, anxiety, and somatic symptoms co-exist from adolescence to midlife. Conclusions The multiple response trajectory analysis confirmed high stability in the co-occurrence of depressive, anxiety, and somatic symptoms from adolescence to midlife. Clinicians should consider these findings to detect symptoms in their earliest phase in order to prevent the development of co-occurring high levels of symptoms.
  • Garcia-Larsen, Vanessa; Del Giacco, Stefano R.; Moreira, Andre; Bonini, Matteo; Haahtela, Tari; Bonini, Sergio; Carlsen, Kai-Hakon; Agache, Ioana; Fonseca, Joao; Papadopoulos, Nikolaos G.; Delgado, Luis (2016)
    Background: Diet has been proposed to modulate the risk of asthma in children and adults. An increasing body of epidemiological studies have been published in the last year investigating the association between dietary intake and asthma. As part of the Evidence-Based Clinical Practice Guideline Task Force on 'Lifestyle Interventions in Allergy and Asthma' funded by the European Academy of Allergy and Clinical Immunology, we will use a systematic approach to review the evidence from published scientific literature on dietary intake and asthma in children and adults. Methods: This systematic review will be carried out following the PRISMA guidelines. The protocol has been published in PROSPERO (CRD42016036078). We will review the evidence from epidemiological studies in children (from the age of 2 years) and adults and dietary intake of foods and nutrients. Discussion: The findings from this review will be used as a reference to inform guideline recommendations.
  • Kotisaari, Kaisa; Virtanen, Pekka; Forss, Nina; Strbian, Daniel; Scheperjans, Filip (2017)
    Purpose: To determine the frequency of emergent imaging findings on head computed tomography (CT) in an adult population of first seizure (FS) patients presenting to an emergency department (ED); and to search for associations between clinical features and emergent imaging findings among these patients. Methods: For this retrospective registry-based study, adult FS patients presenting to Helsinki University Hospital ED in 2006 were identified based on ICD-10 diagnosis. Clinical parameters were extracted from patient records. A neuroradiologist blinded to clinical information reviewed the CT scans for emergent imaging findings prompting changes in acute treatment, predefined as intracranial haemorrhage, acute ischemia, central nervous system infection, mass effect, midline shift, obstructive hydrocephalus and/or brain oedema. Results: 449 FS patients were identified, of which 416 (93%) had undergone emergency CT imaging. Of these, 49 (12%) had emergent imaging findings on non -contrast CT. Logistic regression suggested that headache (odds ratio (OR) 3.62, 95% confidence interval (CI) 1.30-10.12), focal motor sign in the ED (OR 3.23, 95% CI 1.58-6.62), history of malignancy (OR 3.05, 95% CI 1.17-7.92), and altered mental state in the ED (OR 2.27, 95% CI 1.15-4.49) were associated with emergent imaging findings on NCCT. Presence of at least one of these factors had 84% sensitivity for emergent imaging findings. Conclusion: In FS patients, clinical information can be used to guide imaging decisions in the ED. However, if emergency imaging is not performed, urgent outpatient imaging and pre-imaging follow up should be secured. (C) 2017 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
  • Sandell, Mari; Hoppu, Ulla; Mikkila, Vera; Mononen, Nina; Kahonen, Mika; Mannisto, Satu; Ronnemaa, Tapani; Viikari, Jorma; Lehtimaki, Terho; Raitakari, Olli T. (2014)
    Genetic variation in bitter taste receptors, such as hTAS2R38, may affect food preferences and intake. The aim of the present study was to investigate the association between bitter taste receptor haplotypes and the consumption of vegetables, fruits, berries and sweet foods among an adult Finnish population. A cross-sectional design utilizing data from the Cardiovascular Risk in Young Finns cohort from 2007, which consisted of 1,903 men and women who were 30-45 years of age from five different regions in Finland, was employed. DNA was extracted from blood samples, and hTAS2R38 polymorphisms were determined based on three SNPs (rs713598, rs1726866 and rs10246939). Food consumption was assessed with a validated food frequency questionnaire. The prevalence of the bitter taste-sensitive (PAV/PAV) haplotype was 11.3 % and that of the insensitive (AVI/AVI) haplotype was 39.5 % among this Finnish population. PAV homozygotic women consumed fewer vegetables than did the AVI homozygotic women, 269 g/day (SD 131) versus 301 g/day (SD 187), respectively, p = 0.03 (multivariate ANOVA). Furthermore, the intake of sweet foods was higher among the PAV homozygotes of both genders. Fruit and berry consumption did not differ significantly between the haplotypes in either gender. Individuals perceive foods differently, and this may influence their patterns of food consumption. This study showed that the hTAS2R38 taste receptor gene variation was associated with vegetable and sweet food consumption among adults in a Finnish population.
  • Lehtovirta, Suvituuli (Helsingfors universitet, 2015)
    Gynekologiset laskeumat ovat yleisiä ongelmia naisilla. Vaikka niitä pystytään nykyisin hoitamaan operatiivisesti, ne saattavat uusiutua eli residivoida. Tutkimuksen tavoitteena oli selvittää, kuinka suuri residiiviprosentti on Jorvin sairaalassa ja mitkä ovat tärkeimmät residivointiin vaikuttavat potilaan taustatekijät. Tavoitteena oli myös selvittää toimenpidetyypin, leikkaavan lääkärin kokemuksen ja anestesiamuodon vaikutusta residivointiin. Tutkimus tehtiin keräämällä kahden vuoden ajalta laskeumaleikkausaineisto leikkaustietojärjestelmä Operasta ja analysoimalla sitä. 192:n potilaan tutkimuksessa residiiviprosentiksi 3-5 vuoden seuranta-ajalla tuli 11 %. 22:n residiivipotilaan esitiedoista ei löytynyt yhtään merkittävää residiiville altistavaa tekijää. Residiivipotilailta oli poistettu kohtu useammin kuin muilta laskeumapotilailta, mutta tämän todettiin olevan tiastollisesti merkityksetön residiivin kannalta. Toimenpiteistä eturafian todettiin olevan useimmiten uusiva, mikä vastaa aiemmissa tutkimuksissa saatuja tuloksia. Leikkaavan lääkärin kokemuksella ei todettu olevan merkitystä residivointiin. Sen sijaan huomattiin, että paikallispuudutus – vastoin aiempaa käsitystä – johtaa harvemmin residivointiin kuin muu anestesiamuoto. Tätä tietoa voidaan jatkossa hyödyntää pohdittaessa paikallispuudutuksessa tehtävien leikkausten siirtämistä polikliinisiksi.
  • Garcia-Larsen, Vanessa; Arthur, Rhonda; Potts, James F.; Howarth, Peter H.; Ahlström, Matti; Haahtela, Tari Markku Kallevi; Loureiro, Carlos; Bom, Ana Todo; Brozek, Grzegorz; Makowska, Joanna; Kowalski, Marek L.; Thilsing, Trine; Keil, Thomas; Matricardi, Paolo M.; Toren, Kjell; van Zele, Thibaut; Bachert, Claus; Rymarczyk, Barbara; Janson, Christer; Forsberg, Bertil; Nizankowska-Mogilnicka, Ewa; Burney, Peter G. J. (2017)
    Background: Fruits and vegetables are rich in compounds with proposed antioxidant, anti-allergic and anti-inflammatory properties, which could contribute to reduce the prevalence of asthma and allergic diseases. Objective: We investigated the association between asthma, and chronic rhino-sinusitis (CRS) with intake of fruits and vegetables in European adults. Methods: A stratified random sample was drawn from the Global Allergy and Asthma Network of Excellence (GA(2)LEN) screening survey, in which 55,000 adults aged 15-75 answered a questionnaire on respiratory symptoms. Asthma score (derived from self-reported asthma symptoms) and CRS were the outcomes of interest. Dietary intake of 22 subgroups of fruits and vegetables was ascertained using the internationally validated GA(2)LEN Food Frequency Questionnaire. Adjusted associations were examined with negative binomial and multiple regressions. Simes procedure was used to control for multiple testing. Results: A total of 3206 individuals had valid data on asthma and dietary exposures of interest. 22.8% reported having at least 1 asthma symptom (asthma score >= 1), whilst 19.5% had CRS. After adjustment for potential confounders, asthma score was negatively associated with intake of dried fruits (beta-coefficient -2.34;95% confidence interval [CI] -4.09,-0.59), whilst CRS was statistically negatively associated with total intake of fruits (OR 0.73; 95% CI 0.55, 0.97). Conversely, a positive association was observed between asthma score and alliums vegetables (adjusted beta-coefficient 0.23; 95% CI 0.06, 0.40). None of these associations remained statistically significant after controlling for multiple testing. Conclusion and clinical relevance: There was no consistent evidence for an association of asthma or CRS with fruit and vegetable intake in this representative sample of European adults.
  • Garcia-Larsen, Vanessa; Arthur, Rhonda; Potts, James F; Howarth, Peter H; Ahlström, Matti; Haahtela, Tari; Loureiro, Carlos; Bom, Ana T; Brożek, Grzegorz; Makowska, Joanna; Kowalski, Marek L; Thilsing, Trine; Keil, Thomas; Matricardi, Paolo M; Torén, Kjell; van Zele, Thibaut; Bachert, Claus; Rymarczyk, Barbara; Janson, Christer; Forsberg, Bertil; Niżankowska-Mogilnicka, Ewa; Burney, Peter G J (BioMed Central, 2017)
    Abstract Background Fruits and vegetables are rich in compounds with proposed antioxidant, anti-allergic and anti-inflammatory properties, which could contribute to reduce the prevalence of asthma and allergic diseases. Objective We investigated the association between asthma, and chronic rhino-sinusitis (CRS) with intake of fruits and vegetables in European adults. Methods A stratified random sample was drawn from the Global Allergy and Asthma Network of Excellence (GA2LEN) screening survey, in which 55,000 adults aged 15–75 answered a questionnaire on respiratory symptoms. Asthma score (derived from self-reported asthma symptoms) and CRS were the outcomes of interest. Dietary intake of 22 subgroups of fruits and vegetables was ascertained using the internationally validated GA2LEN Food Frequency Questionnaire. Adjusted associations were examined with negative binomial and multiple regressions. Simes procedure was used to control for multiple testing. Results A total of 3206 individuals had valid data on asthma and dietary exposures of interest. 22.8% reported having at least 1 asthma symptom (asthma score ≥1), whilst 19.5% had CRS. After adjustment for potential confounders, asthma score was negatively associated with intake of dried fruits (β-coefficient −2.34; 95% confidence interval [CI] −4.09, −0.59), whilst CRS was statistically negatively associated with total intake of fruits (OR 0.73; 95% CI 0.55, 0.97). Conversely, a positive association was observed between asthma score and alliums vegetables (adjusted β-coefficient 0.23; 95% CI 0.06, 0.40). None of these associations remained statistically significant after controlling for multiple testing. Conclusion and clinical relevance There was no consistent evidence for an association of asthma or CRS with fruit and vegetable intake in this representative sample of European adults.
  • Matricciani, Lisa; Bin, Yu Sun; Lallukka, Tea; Kronholm, Erkki; Dumuid, Dorothea; Paquet, Catherine; Olds, Tim (2017)
    Sleep is important for the physical, social and mental well-being of both children and adults. Over the years, there has been a general presumption that sleep will inevitably decline with the increase in technology and a busy 24-hour modern lifestyle. This narrative review discusses the empirical evidence for secular trends in sleep duration and the implications of these trends. (c) 2017 National Sleep Foundation. Published by Elsevier Inc. All rights reserved.