Browsing by Subject "Borderline Personality Disorder"

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  • Sarparanta, Saana (Helsingin yliopisto, 2015)
    Objective: Major Depressive Disorder (MDD) and Borderline Personality Disorder (BPD) are serious psychiatric disorders highly prevalent in clinical settings, characterized by multiple forms of distress, functional decline, and increased risk of suicide. MDD and BPD often co-occur and the co-occurrence of the disorders is associated with the course of MDD. Early Maladaptive Schemas (EMSs) refer to maladaptive internalized representations of the self in relation to others that develop early in life. EMSs are associated with depressive and BPD symptomatology and symptom severity. However, the associations between EMSs and psychiatric comorbidity have rarely been studied. The aim of the present study was to provide new insight into the comorbidity of BPD and MDD by focusing on the associations between EMSs and BPD symptomatology among depressed inpatient population. Methods: The sample consisted of 43 adult inpatients (29 women and 14 men). BPD symptomatology was measured via Structured Clinical Interview for DSM-III-R Personality Disorders and EMSs via Young Schema Questionnaire-S2-Extended self-report questionnaires. A three-level linear regression model was created to predict self-reported BPD symptomatology: In level 1, linear regression analysis was conducted for each individual EMS separately, EMSs entered as predictors for BPD symptomatology. In level 2, gender, age, education level and employment status were added to the model as covariates. In level 3, also current level of depressive symptoms measured via Center for Epidemiological Studies Depression Scale was added to the model as a covariate. Results and conclusions: Higher scores on 10 of the 18 EMSs were significantly positively associated with elevated self-reported BPD symptomatology. However, only one EMS, Unrelenting Standards and Hypercriticalness, was independently positively associated with self-reported BPD symptomatology and explained variance over the effect of current depressive symptom state, gender, age, education level and employment status. According to the findings of the present study, Unrelenting Standards and Hypercriticalness may act a specific cognitive risk factor for elevated BPD symptomatology and symptom severity among depressed individuals.
  • Baryshnikov, I.; Suvisaari, J.; Aaltonen, K.; Koivisto, Maaria; Naatanen, P.; Karpov, Boris; Melartin, T.; Oksanen, J.; Suominen, K.; Heikkinen, Martti; Paunio, T.; Joffe, G.; Isometsa, E. (2016)
    Background: Distinguishing between symptoms of schizotypal (SPD) and borderline personality disorders (BPD) is often difficult due to their partial overlap and frequent co-occurrence. We investigated correlations in self-reported symptoms of SPD and BPD in questionnaires at the levels of both total scores and individual items, examining overlapping dimensions. Methods: Two questionnaires, the McLean Screening Instrument (MSI) for BPD and the Schizotypal Personality Questionnaire Brief (SPQ-B) for SPD, were filled in by patients with mood disorders (n = 282) from specialized psychiatric care in a study of the Helsinki University Psychiatric Consortium. Correlation coefficients between total scores and individual items of the MSI and SPQ-B were estimated. Multivariate regression analysis (MRA) was conducted to examine the relationships between SPQ-B and MSI. Results: The Spearman's correlation between total scores of the MSI and SPQ-B was strong (rho = 0.616, P <0.005). Items of MSI reflecting disrupted relatedness and affective dysregulation correlated moderately (r(phi) varied between 0.2 and 0.4, P <0.005) with items of SPQ. Items of MSI reflecting behavioural dysregulation correlated only weakly with items of SPQ. In MRA, depressive symptoms, sex and MSI were significant predictors of SPQ-B score, whereas symptoms of anxiety, age and SPQ-B were significant predictors of MSI score. Conclusions: Items reflecting cognitive-perceptual distortions and affective symptoms of BPD appear to overlap with disorganized and cognitive-perceptual symptoms of SPD. Symptoms of depression may aggravate self-reported features of SPQ-B, and symptoms of anxiety features of MSI. Symptoms of behavioural dysregulation of BPD and interpersonal deficits of SPQ appear to be non-overlapping. (C) 2016 Elsevier Masson SAS. All rights reserved.