Browsing by Subject "Contraception"

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  • Korjamo, Riina (2019)
    Kapseleita ja kierukoita tulisi suositella raskaudenkeskeytystä hakevalle naiselle keskeytyksen jälkeiseksi ehkäisyksi, koska ne ovat menetelmistä tehokkaimpia. Kaikkien ehkäisymenetelmien käyttö voidaan aloittaa välittömästi kirurgisen keskeytyksen yhteydessä. Kun keskeytys on lääkkeellinen, pilleri-, rengas-, laastari- ja kapseliehkäisy voidaan aloittaa keskeytyksen alkaessa. Raskauden keskeytyminen tulee varmistaa ennen kierukkaehkäisyn aloitusta.
  • Korjamo, Riina; Mentula, Maarit; Heikinheimo, Oskari (2017)
    Objective: To compare levonorgestrel (LNG) 52-mg intrauterine system (IUS) expulsion rates with fast-track ( Study design: In this pilot trial, we randomized 108 women at Results: We had follow-up data at 3 months and 1 year for 41 (74.5%) and 37 (69.8%) women in the fast-track group and 31 (56.4%) and 28 (52.8%) women in the delayed group. By 3 months, expulsion occurred in six (12.5%) women after fast-track and one (2.3%) woman after delayed insertion [risk ratio (RR) 5.50, 95% confidence interval (CI) 0.69-43.90]; most (n=5) of these were partial expulsions in the fast track group. By 1 year, expulsion had occurred in seven (14.6%) and five (11.5%) women in the fast-track and delayed groups, respectively (RR 1.28, 95% CI 0.44-3.75). We found no differences in rates of vacuum aspiration, residual tissue, infection and bleeding or bleeding patterns within 3 months of insertion. Conclusion: Fast-track insertion of the LNG 52-mg IUS after medical abortion is feasible but may result in higher expulsion rates compared to delayed insertion. Due to lack of statistical power and high lost-to-follow-up rates, we were unable to fully address this question. (C) 2017 Elsevier Inc. All rights reserved.
  • Holopainen, Elina; Vakkilainen, Svetlana; Mäkitie, Outi (2018)
    BackgroundPatients with cartilage-hair hypoplasia (CHH), a rare metaphyseal chondrodysplasia, manifest severe growth failure, variable immunodeficiency and increased risk of malignancies. The impact of CHH on gynecologic and reproductive health is unknown. Vulnerability to genital infections may predispose CHH patients to prolonged human papillomavirus (HPV) infections potentially leading to cervical, vaginal and vulvar cancer.MethodsWe carried out gynecologic evaluation, pelvic ultrasound and laboratory assessment in 19 women with genetically confirmed CHH. All patients were clinically examined and retrospective data were collected from hospital records.ResultsThe women ranged in age from 19.2 to 70.8years (median 40.8years) and in height from 103 to 150cm (median 123cm). All women had undergone normal pubertal development as assessed by breast development according to Tanner scale and by age of menarche (mean 12.5yrs., range 11-14yrs). Despite significant short stature and potentially small pelvic diameters, a well-developed uterus with fairly normal size and shape was found by pelvic ultrasound in mostof the patients. Ovarian follicle reserve, assessed by ultrasound was normal in relation to age in all premenopausal women it could be assessed (12 cases). Anti-Mullerian hormone was normal in relation to age in 17 women (89%). HPV was detected in 44% (8/18) and three women carried more than one HPV serotype; findings did not associate with immunological parameters. Three patients had a concurrent cell atypia in Pap smear.ConclusionsPubertal development, reproductive hormones and ovarian structure and function were usually normal in women with CHH suggesting fairly normal reproductive health. However, the immunodeficiency characteristic to CHH may predispose the patients to HPV infections. High prevalence of HPV infections detected in this series highlights the importance of careful gynecologic follow up of these patients.
  • Holopainen, Elina; Vakkilainen, Svetlana; Mäkitie, Outi (BioMed Central, 2018)
    Abstract Background Patients with cartilage-hair hypoplasia (CHH), a rare metaphyseal chondrodysplasia, manifest severe growth failure, variable immunodeficiency and increased risk of malignancies. The impact of CHH on gynecologic and reproductive health is unknown. Vulnerability to genital infections may predispose CHH patients to prolonged human papillomavirus (HPV) infections potentially leading to cervical, vaginal and vulvar cancer. Methods We carried out gynecologic evaluation, pelvic ultrasound and laboratory assessment in 19 women with genetically confirmed CHH. All patients were clinically examined and retrospective data were collected from hospital records. Results The women ranged in age from 19.2 to 70.8 years (median 40.8 years) and in height from 103 to 150 cm (median 123 cm). All women had undergone normal pubertal development as assessed by breast development according to Tanner scale and by age of menarche (mean 12.5 yrs., range 11–14 yrs). Despite significant short stature and potentially small pelvic diameters, a well-developed uterus with fairly normal size and shape was found by pelvic ultrasound in most of the patients. Ovarian follicle reserve, assessed by ultrasound was normal in relation to age in all premenopausal women it could be assessed (12 cases). Anti-Müllerian hormone was normal in relation to age in 17 women (89%). HPV was detected in 44% (8/18) and three women carried more than one HPV serotype; findings did not associate with immunological parameters. Three patients had a concurrent cell atypia in Pap smear. Conclusions Pubertal development, reproductive hormones and ovarian structure and function were usually normal in women with CHH suggesting fairly normal reproductive health. However, the immunodeficiency characteristic to CHH may predispose the patients to HPV infections. High prevalence of HPV infections detected in this series highlights the importance of careful gynecologic follow up of these patients.
  • Heikinheimo, Oskari; Apter, Dan (2018)
  • Saloranta, Tuire; Heikinheimo, Oskari (2019)
  • Kaislasuo, Janina; Suhonen, Satu; Heikinheimo, Oskari (2016)
    Kie­rukka on pitkä­vai­kut­teinen ehkäi­sy­muoto, jon­ka te­hoon käyt­täjän vir­heet tai unoh­dukset ei­vät vai­kuta. Ikä tai synnyt­tä­neisyys ei­vät vai­kuta kieruk­kaeh­käisyn sopi­vuuteen tai turval­li­suuteen. Kie­rukkaa käyt­tävät nai­set ovat yleensä tyyty­väisiä ehkäi­sy­me­ne­tel­määnsä. Varmis­ta­malla kie­rukan help­po saa­tavuus voi­daan merkit­tä­västi vä­hentää suunnit­te­le­mat­tomia ras­kauksia.
  • Gyllenberg, Frida; Heikinheimo, Oskari (2019)
  • Kaislasuo, Janina; Heikinheimo, Oskari; Suhonen, Satu (2016)