Browsing by Subject "DIDS"

Sort by: Order: Results:

Now showing items 1-3 of 3
  • Mannerström, Rasmus; Hietajärvi, Lauri; Salmela-Aro, Katariina (2021)
    It has been suggested that dual-cycle models of identity formation do not fit well with Erikson’s identity theory and the identity status paradigm due to 1) contradictory statuses, 2) problems with discerning past exploration and 3) ambiguity or limitations of the life domains covered. The present study extended the Dimensions for Identity Development Scale (DIDS) with three additional dimensions suggested previously, examined identity profiles and their transitions over time, their links with psychological well-being and what life domain was associated with “future plans” (N=1294; T1: age=17, 60% female; T2: age=18, 65% female). The results showed that 1) the eight-dimensional model fit the data well longitudinally; 2) six previously reported profiles emerged at both time points with expected links to psychological well-being; 3) as previously speculated, individuals in the (early) closure status had undertaken identity exploration in the past; 4) the previously encountered high commitment-high exploration status (i.e., searching moratorium) seems to be “superficially committed”; and 5) future plans are commonly associated with work life/occupation. Future research would benefit from employing qualitative research to better understand the subjective meanings attached to high commitment-high exploration and by developing new ways to account for quality and different levels of commitment.
  • Koskelainen, A.; Donner, K.; Kalamkarov, G.; Hemilä, S. (Elsevier, 1994)
    The light-sensitive current of dark-adapted rods isolated from the Ambystoma retina was recorded while either the inner or the outer segment (IS or OS) protruding from the suction pipette was exposed to treatments intended to reveal the physiological roles of pH-regulating transport mechanisms. Applied to the IS, both amiloride (presumed to block Na+/H+ exchange, 2 mM) and 4-4′-diisothiocyanatostilbene-2, 2′-disulphonic acid (DIDS) (presumed to block bicarbonate transport, 0.1 mM) generally abolished light sensitivity completely but reversibly, consistent with acidification of the IS. Yet, the circulating (“dark”) current often persisted, implying that the OS was not acidified. Applied to the OS, amiloride depressed but DIDS increased the dark current and photoresponses. Given the fact that the current increases with rising OS-pHi, this suggests alkalinization, which could be due to DIDS inhibiting bicarbonate extrusion by HCO3−/Cl− exchangers in the OS. Consistent with this idea, replacing external Cl− by other anions increased the current as would be expected if HCO3−/Cl− exchange is reversed. We propose that the IS and OS manage their add balances independently and with different sets of transport mechanisms. Acidosis in either compartment suppresses the photosensitivity of the rod, but by differing mechanisms.