Browsing by Subject "SUBSTITUTE"

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  • Koivuniemi, Raili; Hakkarainen, Tiina; Kiiskinen, Jasmi; Kosonen, Mika; Vuola, Jyrki; Valtonen, Jussi; Luukko, Kari; Kavola, Heli; Yliperttula, Marjo (2020)
    Objective: Skin graft donor site management is a concern particularly for elderly patients and patients with poor wound healing competence, and also because donor sites are a source of pain and discomfort. Although different types of dressings exist, there is no consensus regarding optimal dressing type on donor site care to promote healing, reduce pain, and improve patients' comfort. Approach: This prospective, single-center clinical trial evaluated the performance of nanofibrillar cellulose (NFC) wound dressing (FibDex (R) by UPM-Kymmene Corporation) for treatment of donor sites compared with a polylactide-based copolymer dressing. The study enrolled 24 patients requiring skin grafting with mean age of 49 +/- 18. The primary outcome measure was wound healing time. Secondary outcomes, the epithelialization, subjective pain, the scar appearance assessed using the Patient and Observer Scar Assessment Scale (POSAS), and skin elasticity and transepidermal water loss (TEWL), were evaluated at 1 and 6 months postoperatively. Results: No statistically significant differences were observed between NFC and copolymer dressings regarding wound healing time, epithelialization, experience of pain, or TEWL. Significant differences were observed in the POSAS results for thickness and vascularity in the Observer score, in the favor of NFC over copolymer dressing. Moreover, skin elasticity was significantly improved with NFC dressing in terms of viscoelasticity and elastic modulus at 1 month postoperatively. Innovation: NFC dressing is a new, green sustainable product for wound treatment without animal or human-origin components. Conclusion: NFC dressing provides efficient wound healing at skin graft donor sites and is comparable or even preferable compared with the copolymer dressing.
  • Niva, Mari; Vainio, Annukka (2021)
    This study investigated consumers' self-reported past changes and future intentions to change the consumption of beef and alternative, plant- or insect-based protein products. A survey of 18-79-year-old consumers in Finland (N = 1000) was analysed with latent class analysis, and five consumer clusters were identified. The largest cluster (37%) consumed beef, but no alternative protein products; three clusters incorporated alternative protein products in their diets in different ways (in total 55%); and one cluster did not consume beef or alternative proteins (8%). In total 27% of the respondents intended to reduce the consumption of beef in the future, whereas 26% planned to increase the consumption of plant-based and 24% planned to increase the use of insect-based protein products. Multinomial logistic regression indicated that the use of alternative proteins was associated with higher health and sustainability motives, and lower food neophobia. The results suggest that demand for new, more sustainable proteins and protein innovations will grow in the future.