Browsing by Subject "Syphilis"

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  • Kopra, Elisa; Ruokonen, Hellevi; Salo, Tuula (2020)
    Lähes kaikki sukupuolitaudit voivat esiintyä ensimmäisenä myös suun limakalvoilla ja aiheuttaa epäspesifisiä oireita, esimerkiksi haavaumia. Siksi suun ja nielun limakalvojen kliiniseen näkymään ja oireisiin tulee kiinnittää huomiota ja muistaa myös sukupuolitautien mahdollisuus erotusdiagnostiikassa. Kymmenen viime vuoden aikana kuppahavaintojen määrä on lisääntynyt maailmanlaajuisesti, ja tämä on liittynyt erityisesti miesten väliseen seksiin. Primaarivaiheessa kuppa ilmenee suussa aristamattomana, kovareunaisena haavaumana. Diagnosointi on hankalaa tapauksissa, joissa kuppahaavoja esiintyy ainoastaan suuontelossa eikä potilaan anamneesin perusteella herää epäilyä sukupuolitaudin mahdollisuudesta.
  • Myntti, Tarja; Saisto, Terhi; Wartiovaara-Kautto, Ulla (2018)
  • Tiittala, Paula; Ristola, Matti; Liitsola, Kirsi; Ollgren, Jukka; Koponen, Päivikki; Surcel, Heljä-Marja; Hiltunen-Back, Eija; Davidkin, Irja; Kivela, Pia (2018)
    Background: Migrants are considered a key population at risk for sexually transmitted and blood-borne diseases in Europe. Prevalence data to support the design of infectious diseases screening protocols are scarce. We aimed to estimate the prevalence of hepatitis B and C, human immunodefiency virus (HIV) infection and syphilis in specific migrant groups in Finland and to assess risk factors for missed diagnosis. Methods: A random sample of 3000 Kurdish, Russian, or Somali origin migrants in Finland was invited to a migrant population-based health interview and examination survey during 2010-2012. Participants in the health examination were offered screening for hepatitis B and C, HIV and syphilis. Notification prevalence in the National Infectious Diseases Register (NIDR) was compared between participants and non-participants to assess non-participation. Missed diagnosis was defined as test-positive case in the survey without previous notification in NIDR. Inverse probability weighting was used to correct for non-participation. Results: Altogether 1000 migrants were screened for infectious diseases. No difference in the notification prevalence among participants and non-participants was observed. Seroprevalence of hepatitis B surface antigen (HBsAg) was 2.3%, hepatitis C antibodies 1.7%, and Treponema pallidum antibodies 1.3%. No cases of HIV were identified. Of all test-positive cases, 61% (34/56) had no previous notification in NIDR. 48% of HBsAg, 62.5% of anti-HCV and 84.6% of anti-Trpa positive cases had been missed. Among the Somali population (n = 261), prevalence of missed hepatitis B diagnosis was 3.0%. Of the 324 Russian migrants, 3.0% had not been previously diagnosed with hepatitis C and 2.4% had a missed syphilis diagnosis. In multivariable regression model missed diagnosis was associated with migrant origin, living alone, poor self-perceived health, daily smoking, and previous diagnosis of another blood-borne infection. Conclusions: More than half of chronic hepatitis and syphilis diagnoses had been missed among migrants in Finland. Undiagnosed hepatitis B among Somali migrants implies post-migration transmission that could be prevented by enhanced screening and vaccinations. Rate of missed diagnoses among Russian migrants supports implementation of targeted hepatitis and syphilis screening upon arrival and also in later health care contacts. Coverage and up-take of current screening among migrants should be evaluated.
  • Tiittala, Paula; Ristola, Matti; Liitsola, Kirsi; Ollgren, Jukka; Koponen, Päivikki; Surcel, Heljä-Marja; Hiltunen-Back, Eija; Davidkin, Irja; Kivelä, Pia (BioMed Central, 2018)
    Abstract Background Migrants are considered a key population at risk for sexually transmitted and blood-borne diseases in Europe. Prevalence data to support the design of infectious diseases screening protocols are scarce. We aimed to estimate the prevalence of hepatitis B and C, human immunodefiency virus (HIV) infection and syphilis in specific migrant groups in Finland and to assess risk factors for missed diagnosis. Methods A random sample of 3000 Kurdish, Russian, or Somali origin migrants in Finland was invited to a migrant population-based health interview and examination survey during 2010–2012. Participants in the health examination were offered screening for hepatitis B and C, HIV and syphilis. Notification prevalence in the National Infectious Diseases Register (NIDR) was compared between participants and non-participants to assess non-participation. Missed diagnosis was defined as test-positive case in the survey without previous notification in NIDR. Inverse probability weighting was used to correct for non-participation. Results Altogether 1000 migrants were screened for infectious diseases. No difference in the notification prevalence among participants and non-participants was observed. Seroprevalence of hepatitis B surface antigen (HBsAg) was 2.3%, hepatitis C antibodies 1.7%, and Treponema pallidum antibodies 1.3%. No cases of HIV were identified. Of all test-positive cases, 61% (34/56) had no previous notification in NIDR. 48% of HBsAg, 62.5% of anti-HCV and 84.6% of anti-Trpa positive cases had been missed. Among the Somali population (n = 261), prevalence of missed hepatitis B diagnosis was 3.0%. Of the 324 Russian migrants, 3.0% had not been previously diagnosed with hepatitis C and 2.4% had a missed syphilis diagnosis. In multivariable regression model missed diagnosis was associated with migrant origin, living alone, poor self-perceived health, daily smoking, and previous diagnosis of another blood-borne infection. Conclusions More than half of chronic hepatitis and syphilis diagnoses had been missed among migrants in Finland. Undiagnosed hepatitis B among Somali migrants implies post-migration transmission that could be prevented by enhanced screening and vaccinations. Rate of missed diagnoses among Russian migrants supports implementation of targeted hepatitis and syphilis screening upon arrival and also in later health care contacts. Coverage and up-take of current screening among migrants should be evaluated.
  • Vuorinen, Heikki S. (2021)
    Pandemiat astuivat näyttämölle yhteiskuntien verkostoiduttua maailmanlaajuisesti viime vuosisatoina. Yersinia pestis, Treponema pallidum, Vibrio cholerae, influenssavirus, HI-virus ja SARS-CoV-2-virus ovat pandemian aiheuttaneita mikrobeja, joihin on ollut pakko sopeutua historian kuluessa. Väestön rokottaminen on noussut entistä tärkeämmäksi keinoksi selviytyä pandemioista. Merkittävin tekijä yhteiskuntien sopeutumisessa pandemioihin on ollut kansainvälisen yhteistyön kehittyminen sen jälkeen, kun maailma alkoi kutoutua yhä tiiviimmäksi verkostoksi 1800-luvulta lähtien. Yhteistyön esteenä on ollut nationalismi ja siihen tukeutuva ja siitä kumpuava kansallisvaltio.
  • Koivisto, Veikko; Ranki-Pesonen, Marjut; Kontula, Kimmo (2016)
  • Hiltunen-Back, Eija; Puolakkainen, Mirja (2018)
    Tippuritartunnat ovat lisääntyneet. Niitä ei voi kliinisesti erottaa klamydia- tartunnoista. Oireettomuus on yleistä kummassakin taudissa. Ne tulee testata yhtä aikaa. Genitaalialueen klamydiainfektio hoidetaan atsitromysiinillä tai doksisykliinillä ja… genitaalialueen ulkopuoliset infektiot doksisykliinillä. Tippurin hoito toteutetaan herkkyysmäärityksen mukaan. Viljelyn merkitys diagnostiikassa korostuu.