Browsing by Subject "extremely low birth weight"

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  • Mathewson, Karen J.; Pyhälä, Riikka; Hovi, Petteri; Räikkönen, Katri; Van Lieshout, Ryan J.; Boyle, Michael H.; Saigal, Saroj; Morrison, Katherine M.; Kajantie, Eero; Schmidt, Louis A. (2015)
    Background. Adults born extremely preterm appear to have more difficulty managing the stresses of early adulthood than their term-born peers. Objective. To examine the effects of being born at extremely low birth weight (ELBW; birth weight < 1000 g) versus at full term on cardiovascular responses to stress. Method. Cardiovascular responses were elicited during administration of a widely used laboratory stressor, the Trier Social Stress Test (TSST). Results. Term-born adults exhibited a larger decrease in total peripheral resistance and larger increase in cardiac output for TSST performance, reflecting greater resilience, than did ELBW adults. Furthermore, in ELBW participants but not controls, cardiovascular responses were correlated with anxiety, suggesting that their responses reflected feelings of stress. Conclusions. Skills-training and practice with relevant stressors may be necessary to increase the personal resources of ELBW participants for managing stress as they transition to adulthood.
  • Uusitalo, Karoliina; Haataja, Leena; Nyman, Anna; Ripatti, Liisi; Huhtala, Mira; Rautava, Päivi; Lehtonen, Liisa; Parkkola, Riitta; Lahti, Katri; Koivisto, Mari; Setänen, Sirkku (2020)
    Objective To evaluate the rate of developmental coordination disorder (DCD) and its correlation to cognition and self-experienced health-related quality of life (HRQoL) in children born very preterm. Design Prospective follow-up study. Setting Regional population of children born very preterm in Turku University Hospital, Finland, in 2001-2006. Patients A total of 170 children born very preterm were followed up until 11 years of age. Main outcome measures Motor and cognitive outcomes were evaluated using the Movement Assessment Battery for Children -Second Edition (Movement ABC-2) and the Wechsler Intelligence Scale for Children -Fourth Edition, respectively, and HRQoL using the 17-Dimensional Illustrated Questionnaire (17D). The Touwen neurological examination was performed to exclude other neurological conditions affecting the motor outcome. Results Eighteen children born very preterm (17 boys) (11.3%) had DCD, defined as Movement ABC-2 total test score ≤5th percentile. A positive correlation between motor and cognitive outcome (r=0.22, p=0.006) was found. Children born very preterm with DCD had lower cognitive scores than those without DCD (Full-Scale IQ mean 76.8 vs 91.6, p=0.001). Moreover, children born very preterm with DCD reported lower HRQoL than children born very preterm without motor impairment (17D mean 0.93 vs 0.96, p=0.03). However, HRQoL was higher in this group of children born very preterm compared with population-based normative test results (p