Infant Growth after Preterm Birth and Mental Health in Young Adulthood

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Sammallahti , S , Lahti , M , Pyhala , R , Lahti , J , Pesonen , A-K , Heinonen , K , Hovi , P , Eriksson , J G , Strang-Karlsson , S , Jarvenpaa , A-L , Andersson , S , Kajantie , E & Räikkönen , K 2015 , ' Infant Growth after Preterm Birth and Mental Health in Young Adulthood ' , PLoS One , vol. 10 , no. 9 , e0137092 .

Title: Infant Growth after Preterm Birth and Mental Health in Young Adulthood
Author: Sammallahti, Sara; Lahti, Marius; Pyhala, Riikka; Lahti, Jari; Pesonen, Anu-Katriina; Heinonen, Kati; Hovi, Petteri; Eriksson, Johan G.; Strang-Karlsson, Sonja; Jarvenpaa, Anna-Liisa; Andersson, Sture; Kajantie, Eero; Räikkönen, Katri
Contributor organization: Clinicum
Behavioural Sciences
University of Helsinki
Children's Hospital
Johan Eriksson / Principal Investigator
Department of General Practice and Primary Health Care
Lastentautien yksikkö
HUS Children and Adolescents
Developmental Psychology Research Group
Date: 2015-09-01
Language: eng
Number of pages: 13
Belongs to series: PLoS One
ISSN: 1932-6203
Abstract: Objectives Faster growth after preterm birth benefits long-term cognitive functioning. Whether these benefits extend to mental health remains largely unknown. We examined if faster growth in infancy is associated with better self-reported mental health in young adults born preterm at very low birth weight (VLBW) ( Study Design As young adults, participants of the Helsinki Study of Very Low Birth Weight Adults self-reported symptoms of depression and attention deficit/hyperactivity disorder (ADHD) (n = 157) and other psychiatric problems (n = 104). As main predictors of mental health outcomes in linear regression models, we used infant weight, length, and head circumference at birth, term, and 12 months of corrected age, and growth between these time points. Growth data were collected from records and measures at term and at 12 months of corrected age were interpolated. Additionally, we examined the moderating effects of intrauterine growth restriction. Results Size at birth, term, or 12 months of corrected age, or growth between these time points were not associated with mental health outcomes (p-values >0.05). Intrauterine growth restriction did not systematically moderate any associations. Conclusions Despite the high variability in early growth of VLBW infants, the previously described association between slow growth in infancy and poorer cognitive functioning in later life is not reflected in symptoms of depression, ADHD, and other psychiatric problems. This suggests that the development of cognitive and psychiatric problems may have dissimilar critical periods in VLBW infants.
3123 Gynaecology and paediatrics
3124 Neurology and psychiatry
515 Psychology
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion

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