Delineating Margins of Lentigo Maligna Using a Hyperspectral Imaging System

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dc.contributor.author Neittaanmäki-Perttu, Noora
dc.contributor.author Gronroos, Mari
dc.contributor.author Jeskanen, Leila
dc.contributor.author Polonen, Ilkka
dc.contributor.author Ranki, Annamari
dc.contributor.author Saksela, Olli
dc.contributor.author Snellman, Erna
dc.date.accessioned 2016-05-11T14:05:01Z
dc.date.available 2016-05-11T14:05:01Z
dc.date.issued 2015
dc.identifier.citation Neittaanmäki-Perttu , N , Gronroos , M , Jeskanen , L , Polonen , I , Ranki , A , Saksela , O & Snellman , E 2015 , ' Delineating Margins of Lentigo Maligna Using a Hyperspectral Imaging System ' , Acta Dermato-Venereologica , vol. 95 , no. 5 , pp. 549-552 . https://doi.org/10.2340/00015555-2010
dc.identifier.other PURE: 49803018
dc.identifier.other PURE UUID: c37a1368-7346-441a-8f33-f27e1132052c
dc.identifier.other WOS: 000355057100007
dc.identifier.other Scopus: 84928170395
dc.identifier.uri http://hdl.handle.net/10138/161811
dc.description.abstract Lentigo maligna (LM) is an in situ form of melanoma which can progress into invasive lentigo maligna melanoma (LMM). Variations in the pigmentation and thus visibility of the tumour make assessment of lesion borders challenging. We tested hyperspectral imaging system (HIS) in in vivo preoperative delineation of LM and LMM margins. We compared lesion margins delineated by HIS with those estimated clinically, and confirmed histologically. A total of 14 LMs and 5 LIVIMs in 19 patients were included. HIS analysis matched the histopathological analysis in 18/19 (94.7%) cases while in 1/19 (5.3%) cases HIS showed lesion extension not confirmed by histopathology (false positives). Compared to clinical examination, HIS defined lesion borders more accurately in 10/19 (52.6%) of cases (wider, n=7 or smaller, n=3) while in 8/19 (42.1%) cases lesion borders were the same as delineated clinically as confirmed histologically. Thus, HIS is useful for the detection of subclinical LM/LMM borders. en
dc.format.extent 4
dc.language.iso eng
dc.relation.ispartof Acta Dermato-Venereologica
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject lentigo maligna
dc.subject lentigo maligna melanoma
dc.subject tumour margin assessment
dc.subject hyperspectral imaging
dc.subject CONFOCAL MICROSCOPY
dc.subject SKIN-CANCER
dc.subject MELANOMA
dc.subject MANAGEMENT
dc.subject ALGORITHM
dc.subject SURGERY
dc.subject CARE
dc.subject 3121 General medicine, internal medicine and other clinical medicine
dc.title Delineating Margins of Lentigo Maligna Using a Hyperspectral Imaging System en
dc.type Article
dc.contributor.organization Department of Dermatology, Allergology and Venereology
dc.contributor.organization Clinicum
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.2340/00015555-2010
dc.relation.issn 0001-5555
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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