Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice

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Kakkola , L , Denisova , O V , Tynell , J , Viiliainen , J , Ysenbaert , T , Matos , R C , Nagaraj , A , Öhman , T , Kuivanen , S , Paavilainen , H , Feng , L , Yadav , B , Julkunen , I , Vapalahti , O , Hukkanen , V , Stenman , J , Aittokallio , T , Verschuren , E W , Ojala , P M , Nyman , T , Saelens , X , Dzeyk , K & Kainov , D E 2013 , ' Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice ' , Cell Death and Disease , vol. 4 , no. Article Number: e742 . https://doi.org/10.1038/cddis.2013.267

Title: Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice
Author: Kakkola, L.; Denisova, O. V.; Tynell, J.; Viiliainen, J.; Ysenbaert, T.; Matos, R. C.; Nagaraj, A.; Öhman, Tiina; Kuivanen, S.; Paavilainen, H.; Feng, L.; Yadav, B.; Julkunen, I.; Vapalahti, O.; Hukkanen, V.; Stenman, J.; Aittokallio, T.; Verschuren, E. W.; Ojala, P. M.; Nyman, T.; Saelens, X.; Dzeyk, K.; Kainov, D. E.
Contributor: University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute of Biotechnology
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute of Biotechnology
University of Helsinki, Haartman Institute
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Haartman Institute
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute of Biotechnology
University of Helsinki, Institute of Biotechnology
University of Helsinki, Institute for Molecular Medicine Finland
Date: 2013-07
Language: eng
Number of pages: 11
Belongs to series: Cell Death and Disease
ISSN: 2041-4889
URI: http://hdl.handle.net/10138/161903
Subject: innate immunity
apoptosis
Bcl-xL
infection
cytokines
virus
BCL-X-L
EPITHELIAL-CELLS
HUMAN PLATELETS
INFLUENZA
DEATH
INDUCTION
PROTEIN
POTENT
SALIPHENYLHALAMIDE
REPLICATION
3111 Biomedicine
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