Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice

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http://hdl.handle.net/10138/161903

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Kakkola , L , Denisova , O V , Tynell , J , Viiliainen , J , Ysenbaert , T , Matos , R C , Nagaraj , A , Öhman , T , Kuivanen , S , Paavilainen , H , Feng , L , Yadav , B , Julkunen , I , Vapalahti , O , Hukkanen , V , Stenman , J , Aittokallio , T , Verschuren , E W , Ojala , P M , Nyman , T , Saelens , X , Dzeyk , K & Kainov , D E 2013 , ' Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice ' , Cell Death and Disease , vol. 4 , no. Article Number: e742 . https://doi.org/10.1038/cddis.2013.267

Titel: Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice
Författare: Kakkola, L.; Denisova, O. V.; Tynell, J.; Viiliainen, J.; Ysenbaert, T.; Matos, R. C.; Nagaraj, A.; Öhman, Tiina; Kuivanen, S.; Paavilainen, H.; Feng, L.; Yadav, B.; Julkunen, I.; Vapalahti, O.; Hukkanen, V.; Stenman, J.; Aittokallio, T.; Verschuren, E. W.; Ojala, P. M.; Nyman, T.; Saelens, X.; Dzeyk, K.; Kainov, D. E.
Upphovmannens organisation: Institute for Molecular Medicine Finland
Institute of Biotechnology
Haartman Institute (-2014)
Department of Virology
Human Parvoviruses: Epidemiology, Molecular Biology and Clinical Impact
Bioinformatics
Viral Zoonosis Research Unit
Lung Cancer Model Systems
Datum: 2013-07
Språk: eng
Sidantal: 11
Tillhör serie: Cell Death and Disease
ISSN: 2041-4889
DOI: https://doi.org/10.1038/cddis.2013.267
Permanenta länken (URI): http://hdl.handle.net/10138/161903
Subject: innate immunity
apoptosis
Bcl-xL
infection
cytokines
virus
BCL-X-L
EPITHELIAL-CELLS
HUMAN PLATELETS
INFLUENZA
DEATH
INDUCTION
PROTEIN
POTENT
SALIPHENYLHALAMIDE
REPLICATION
3111 Biomedicine
Referentgranskad: Ja
Licens: cc_by
Användningsbegränsning: openAccess
Parallelpublicerad version: publishedVersion


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