Circulating tumor DNA in early-stage breast cancer : personalized biomarkers for occult metastatic disease and risk of relapse?

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dc.contributor University of Helsinki, Institute for Molecular Medicine Finland en
dc.contributor University of Helsinki, Institute for Molecular Medicine Finland en
dc.contributor University of Helsinki, Institute for Molecular Medicine Finland en
dc.contributor.author af Hallstrom, Taija M.
dc.contributor.author Puhka, Maija
dc.contributor.author Kallioniemi, Olli
dc.date.accessioned 2016-05-12T11:06:01Z
dc.date.available 2016-05-12T11:06:01Z
dc.date.issued 2015-08
dc.identifier.citation af Hallstrom , T M , Puhka , M & Kallioniemi , O 2015 , ' Circulating tumor DNA in early-stage breast cancer : personalized biomarkers for occult metastatic disease and risk of relapse? ' , EMBO molecular medicine , vol. 7 , no. 8 , pp. 994-995 . https://doi.org/10.15252/emmm.201505332 en
dc.identifier.issn 1757-4676
dc.identifier.other PURE: 53116912
dc.identifier.other PURE UUID: 042d5fd9-ccfc-4b23-b3b1-83df74bacf99
dc.identifier.other WOS: 000359070600003
dc.identifier.other Scopus: 84938416054
dc.identifier.other ORCID: /0000-0002-6445-1017/work/68614852
dc.identifier.uri http://hdl.handle.net/10138/161935
dc.description.abstract The availability of blood-based markers topredict response of a solid tumor to treatment, estimate patient prognosis and diagnose relapse well before clinical symptoms arise, is a long-standing hope in clinical oncology. Ideally, assays designed to provide such information should be inexpensive (at least in the foreseeable future), simple, and, of course, predictive of the clinical evolution of the disease. While early research focused on circulating glycosylated tumor-derived protein biomarkers, the focus is now rapidly shifting to new opportunities, such as circulating tumor cells, extracellular vesicles, micro-RNAs and cancer-derived cell-free DNA a.k.a. circulating tumor-derived DNA (ctDNA). en
dc.format.extent 2
dc.language.iso eng
dc.relation.ispartof EMBO molecular medicine
dc.rights en
dc.subject 3111 Biomedicine en
dc.title Circulating tumor DNA in early-stage breast cancer : personalized biomarkers for occult metastatic disease and risk of relapse? en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.15252/emmm.201505332
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/publishedVersion
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