Microscopy Image Browser : A Platform for Segmentation and Analysis of Multidimensional Datasets

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http://hdl.handle.net/10138/161956

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Belevich , I , Joensuu , M , Kumar , D , Vihinen , H & Jokitalo , E 2016 , ' Microscopy Image Browser : A Platform for Segmentation and Analysis of Multidimensional Datasets ' , PLoS Biology , vol. 14 , no. 1 , 1002340 . https://doi.org/10.1371/journal.pbio.1002340

Title: Microscopy Image Browser : A Platform for Segmentation and Analysis of Multidimensional Datasets
Author: Belevich, Ilya; Joensuu, Merja; Kumar, Darshan; Vihinen, Helena; Jokitalo, Eija
Contributor: University of Helsinki, Institute of Biotechnology
University of Helsinki, Institute of Biotechnology
University of Helsinki, Institute of Biotechnology
University of Helsinki, Institute of Biotechnology
University of Helsinki, Institute of Biotechnology
Date: 2016-01
Language: eng
Number of pages: 13
Belongs to series: PLoS Biology
ISSN: 1545-7885
URI: http://hdl.handle.net/10138/161956
Abstract: Understanding the structure-function relationship of cells and organelles in their natural context requires multidimensional imaging. As techniques for multimodal 3-D imaging have become more accessible, effective processing, visualization, and analysis of large datasets are posing a bottleneck for the workflow. Here, we present a new software package for high-performance segmentation and image processing of multidimensional datasets that improves and facilitates the full utilization and quantitative analysis of acquired data, which is freely available from a dedicated website. The open-source environment enables modification and insertion of new plug-ins to customize the program for specific needs. We provide practical examples of program features used for processing, segmentation and analysis of light and electron microscopy datasets, and detailed tutorials to enable users to rapidly and thoroughly learn how to use the program.
Subject: 3D VISUALIZATION
CELLS
BIOLOGY
MOUSE
DEAD
1182 Biochemistry, cell and molecular biology
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