The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

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Middeldorp , C M , de Moor , M H M , McGrath , L M , Gordon , S D , Blackwood , D H , Costa , P T , Terracciano , A , Krueger , R F , de Geus , E J C , Nyholt , D R , Tanaka , T , Esko , T , Madden , P A F , Derringer , J , Amin , N , Willemsen , G , Hottenga , J-J , Distel , M A , Uda , M , Sanna , S , Spinhoven , P , Hartman , C A , Ripke , S , Sullivan , P F , Realo , A , Allik , J , Heath , A C , Pergadia , M L , Agrawal , A , Lin , P , Grucza , R A , Widen , E , Cousminer , D L , Eriksson , J G , Palotie , A , Barnett , J H , Lee , P H , Luciano , M , Tenesa , A , Davies , G , Lopez , L M , Hansell , N K , Medland , S E , Ferrucci , L , Schlessinger , D , Montgomery , G W , Wright , M J , Aulchenko , Y S , Janssens , A C J W , Oostra , B A , Metspalu , A , Abecasis , G R , Deary , I J , Räikkönen , K , Bierut , L J , Martin , N G , Wray , N R , van Duijn , C M , Smoller , J W , Penninx , B W J H & Boomsma , D I 2011 , ' The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data ' , Translational Psychiatry , vol. 1 , 50 . https://doi.org/10.1038/tp.2011.45

Title: The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data
Author: Middeldorp, C. M.; de Moor, M. H. M.; McGrath, L. M.; Gordon, S. D.; Blackwood, D. H.; Costa, P. T.; Terracciano, A.; Krueger, R. F.; de Geus, E. J. C.; Nyholt, D. R.; Tanaka, T.; Esko, T.; Madden, P. A. F.; Derringer, J.; Amin, N.; Willemsen, G.; Hottenga, J-J; Distel, M. A.; Uda, M.; Sanna, S.; Spinhoven, P.; Hartman, C. A.; Ripke, S.; Sullivan, P. F.; Realo, A.; Allik, J.; Heath, A. C.; Pergadia, M. L.; Agrawal, A.; Lin, P.; Grucza, R. A.; Widen, E.; Cousminer, D. L.; Eriksson, J. G.; Palotie, A.; Barnett, J. H.; Lee, P. H.; Luciano, M.; Tenesa, A.; Davies, G.; Lopez, L. M.; Hansell, N. K.; Medland, S. E.; Ferrucci, L.; Schlessinger, D.; Montgomery, G. W.; Wright, M. J.; Aulchenko, Y. S.; Janssens, A. C. J. W.; Oostra, B. A.; Metspalu, A.; Abecasis, G. R.; Deary, I. J.; Räikkönen, Katri; Bierut, L. J.; Martin, N. G.; Wray, N. R.; van Duijn, C. M.; Smoller, J. W.; Penninx, B. W. J. H.; Boomsma, D. I.
Other contributor: University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Department of General Practice and Primary Health Care
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Behavioural Sciences







Date: 2011
Language: eng
Number of pages: 8
Belongs to series: Translational Psychiatry
ISSN: 2158-3188
DOI: https://doi.org/10.1038/tp.2011.45
URI: http://hdl.handle.net/10138/162755
Subject: bipolar disorder
genetic correlation
genome-wide association
polygenic score analysis
personality-major depression
GENOTYPE IMPUTATION
ANXIETY DISORDERS
5-FACTOR MODEL
TWIN
POPULATION
HERITABILITY
METAANALYSIS
SAMPLE
SCHIZOPHRENIA
EPIDEMIOLOGY
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