Narrowband Ultraviolet B Exposures Maintain Vitamin D Levels During Winter : A Randomized Controlled Trial

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http://hdl.handle.net/10138/163515

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Karppinen , T , Ala-Houhala , M , Ylianttila , L , Kautiainen , H , Viljakainen , H , Reunala , T & Snellman , E 2016 , ' Narrowband Ultraviolet B Exposures Maintain Vitamin D Levels During Winter : A Randomized Controlled Trial ' , Acta Dermato-Venereologica , vol. 96 , no. 4 , pp. 490-493 . https://doi.org/10.2340/00015555-2269

Title: Narrowband Ultraviolet B Exposures Maintain Vitamin D Levels During Winter : A Randomized Controlled Trial
Author: Karppinen, Toni; Ala-Houhala, Meri; Ylianttila, Lasse; Kautiainen, Hannu; Viljakainen, Heli; Reunala, Timo; Snellman, Erna
Contributor: University of Helsinki, Department of General Practice and Primary Health Care
University of Helsinki, Clinicum
Date: 2016
Language: eng
Number of pages: 4
Belongs to series: Acta Dermato-Venereologica
ISSN: 0001-5555
URI: http://hdl.handle.net/10138/163515
Abstract: Exposure to solar ultraviolet B radiation during the summer months is the main source of vitamin D (VD) for people living in northern latitudes. The aim of this study was to determine whether artificial narrowband ultraviolet B (NB-UVB) whole-body exposures could maintain VD levels in winter. The intervention group received 2 standard erythema doses (SEDs) of NB-UVB exposures every second week from October 2013 to April 2014. In October 2013 serum 25-hydroxyvitamin D concentrations were 78.3 nmol/l in the intervention group (n=16) and 76.8 nmol/l in the control group (n=18). By April 2014 the concentrations had increased by 11.7 nmol/l (p=0.029) in the intervention group and decreased by 11.1 nmol/l (p=0.022) in the control group. The baseline VD concentration showed a negative correlation (p=0.012) with body mass index (BMI). In conclusion, a suberythemal NB-UVB dose of 2 SED every second week maintains and even increases serum VD concentrations during the winter. A high BMI seems to predispose subjects to low levels of VD.
Subject: 25-hydroxyvitamin D
ultraviolet B
narrow-band ultraviolet B
body mass index
SERUM 25-HYDROXYVITAMIN D
IMMUNE PROTECTION FACTORS
D SUPPLEMENTATION
CLINICAL-TRIAL
PHOTOTHERAPY
SUFFICIENT
PSORIASIS
HUMANS
3121 General medicine, internal medicine and other clinical medicine
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