Use of anti-dementia drugs in home care and residential care and associations with neuropsychiatric symptoms : a cross-sectional study

Näytä kaikki kuvailutiedot



Pysyväisosoite

http://hdl.handle.net/10138/164079

Lähdeviite

Kuronen , M , Koponen , H , Nykanen , I , Karppi , P & Hartikainen , S 2015 , ' Use of anti-dementia drugs in home care and residential care and associations with neuropsychiatric symptoms : a cross-sectional study ' , BMC Geriatrics , vol. 15 , 100 . https://doi.org/10.1186/s12877-015-0102-4

Julkaisun nimi: Use of anti-dementia drugs in home care and residential care and associations with neuropsychiatric symptoms : a cross-sectional study
Tekijä: Kuronen, Marja; Koponen, Hannu; Nykanen, Irma; Karppi, Pertti; Hartikainen, Sirpa
Tekijän organisaatio: Clinicum
Department of Psychiatry
HUS Psychiatry
Päiväys: 2015-08-13
Kieli: eng
Sivumäärä: 8
Kuuluu julkaisusarjaan: BMC Geriatrics
ISSN: 1471-2318
DOI-tunniste: https://doi.org/10.1186/s12877-015-0102-4
URI: http://hdl.handle.net/10138/164079
Tiivistelmä: Background: The number of people with dementia is increasing alongside the aging population, and most of these patients manifest with neuropsychiatric symptoms (NPS). The objective of this study was to investigate anti-dementia drug use and its associations with NPS. Methods: Questionnaires on demographic information, current drug use, activities of daily living and NPS were sent to all municipal home care producers and to all institutions providing long-term residential care in the South Savo Hospital District, Finland. Results: The study population comprised 2821 persons. Their mean age was 81 years and 68 % were female. Dementia had been diagnosed in 31 % (n = 410) in home care and in 56 % (n = 774) in residential care. Anti-dementia drugs were used by 69 % of patients with dementia. Hyperactivity symptoms were common in residential care patients (n = 456, 33 %), while problems with mood and apathy dominated in home care patients (n = 486, 54 %). In multivariate regression analysis, the mood symptoms and apathy subgroup was associated with use of an acetylcholinesterase inhibitor (AChEI) (OR 1.44; 95 % Cl 1.03-2.02), memantine (OR 1.77, 95 % Cl 1.15-2.72) or their combinations (OR 1.56, 95 % Cl 1.03-2.34). Hyperactivity symptoms were associated with combination therapy of this type (OR 2.03, 95 % Cl 1.36-2.34). Conclusions: The use of anti-dementia drugs was common in both care settings. The use of any anti-dementia drug or combination was associated with the mood and apathy subgroup. The hyperactivity subgroup was associated with combination use of memantine and AChEI.
Avainsanat: SEVERE ALZHEIMERS-DISEASE
PSYCHOLOGICAL SYMPTOMS
BEHAVIORAL-PROBLEMS
GERIATRIC CARE
OLD-PEOPLE
DEMENTIA
MANAGEMENT
CONSORTIUM
MEMANTINE
MODERATE
3121 General medicine, internal medicine and other clinical medicine
Vertaisarvioitu: Kyllä
Tekijänoikeustiedot: cc_by
Pääsyrajoitteet: openAccess
Rinnakkaistallennettu versio: publishedVersion


Tiedostot

Latausmäärä yhteensä: Ladataan...

Tiedosto(t) Koko Formaatti Näytä
s12877_015_0102_4.pdf 441.9KB PDF Avaa tiedosto

Viite kuuluu kokoelmiin:

Näytä kaikki kuvailutiedot