Job Strain and Cardiovascular Disease Risk Factors : Meta-Analysis of Individual-Participant Data from 47,000 Men and Women

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http://hdl.handle.net/10138/165116

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Nyberg , S T , Fransson , E I , Heikkila , K , Alfredsson , L , Casini , A , Clays , E , De Bacquer , D , Dragano , N , Erbel , R , Ferrie , J E , Hamer , M , Joeckel , K-H , Kittel , F , Knutsson , A , Ladwig , K-H , Lunau , T , Marmot , M G , Nordin , M , Rugulies , R , Siegrist , J , Steptoe , A , Westerholm , P J M , Westerlund , H , Theorell , T , Brunner , E J , Singh-Manoux , A , Batty , G D & Kivimaki , M 2013 , ' Job Strain and Cardiovascular Disease Risk Factors : Meta-Analysis of Individual-Participant Data from 47,000 Men and Women ' , PLoS One , vol. 8 , no. 6 , 67323 . https://doi.org/10.1371/journal.pone.0067323

Title: Job Strain and Cardiovascular Disease Risk Factors : Meta-Analysis of Individual-Participant Data from 47,000 Men and Women
Author: Nyberg, Solja T.; Fransson, Eleonor I.; Heikkila, Katriina; Alfredsson, Lars; Casini, Annalisa; Clays, Els; De Bacquer, Dirk; Dragano, Nico; Erbel, Raimund; Ferrie, Jane E.; Hamer, Mark; Joeckel, Karl-Heinz; Kittel, France; Knutsson, Anders; Ladwig, Karl-Heinz; Lunau, Thorsten; Marmot, Michael G.; Nordin, Maria; Rugulies, Reiner; Siegrist, Johannes; Steptoe, Andrew; Westerholm, Peter J. M.; Westerlund, Hugo; Theorell, Tores; Brunner, Eric J.; Singh-Manoux, Archana; Batty, G. David; Kivimaki, Mika
Contributor: University of Helsinki, Behavioural Sciences
Date: 2013-06-20
Language: eng
Number of pages: 6
Belongs to series: PLoS One
ISSN: 1932-6203
URI: http://hdl.handle.net/10138/165116
Abstract: Background: Job strain is associated with an increased coronary heart disease risk, but few large-scale studies have examined the relationship of this psychosocial characteristic with the biological risk factors that potentially mediate the job strain - heart disease association. Methodology and Principal Findings: We pooled cross-sectional, individual-level data from eight studies comprising 47,045 participants to investigate the association between job strain and the following cardiovascular disease risk factors: diabetes, blood pressure, pulse pressure, lipid fractions, smoking, alcohol consumption, physical inactivity, obesity, and overall cardiovascular disease risk as indexed by the Framingham Risk Score. In age-, sex-, and socioeconomic status-adjusted analyses, compared to those without job strain, people with job strain were more likely to have diabetes (odds ratio 1.29; 95% CI: 1.11-1.51), to smoke (1.14; 1.08-1.20), to be physically inactive (1.34; 1.26-1.41), and to be obese (1.12; 1.04-1.20). The association between job strain and elevated Framingham risk score (1.13; 1.03-1.25) was attributable to the higher prevalence of diabetes, smoking and physical inactivity among those reporting job strain. Conclusions: In this meta-analysis of work-related stress and cardiovascular disease risk factors, job strain was linked to adverse lifestyle and diabetes. No association was observed between job strain, clinic blood pressure or blood lipids.
Subject: CORONARY-HEART-DISEASE
AMBULATORY BLOOD-PRESSURE
3-YEAR FOLLOW-UP
WHITEHALL-II
WORK STRESS
COHORT
INEQUALITIES
MORTALITY
SWEDISH
PROFILE
3142 Public health care science, environmental and occupational health
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