High temperature and bacteriophages can indirectly select for bacterial pathogenicity in environmental reservoirs

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dc.contributor University of Helsinki, University of Jyväskylä en
dc.contributor University of Helsinki, Biosciences en
dc.contributor.author Friman, Ville-Petri
dc.contributor.author Hiltunen, Teppo
dc.contributor.author Jalasvuori, Matti
dc.contributor.author Lindstedt, Carita
dc.contributor.author Laanto, Elina
dc.contributor.author Örmälä, Anni-Maria
dc.contributor.author Laakso, Jouni
dc.contributor.author Mappes, Johanna
dc.contributor.author Bamford, Jaana
dc.date.accessioned 2016-08-12T10:22:01Z
dc.date.available 2016-08-12T10:22:01Z
dc.date.issued 2011
dc.identifier.citation Friman , V-P , Hiltunen , T , Jalasvuori , M , Lindstedt , C , Laanto , E , Örmälä , A-M , Laakso , J , Mappes , J & Bamford , J 2011 , ' High temperature and bacteriophages can indirectly select for bacterial pathogenicity in environmental reservoirs ' , PLoS One , vol. 6 , no. 3 , pp. e17651 . https://doi.org/10.1371/journal.pone.0017651 en
dc.identifier.issn 1932-6203
dc.identifier.other PURE: 13736543
dc.identifier.other PURE UUID: 53855aba-bd4a-42eb-95dc-69871213d55a
dc.identifier.other WOS: 000288513900015
dc.identifier.other Scopus: 79952642773
dc.identifier.other ORCID: /0000-0001-8245-9912/work/30453714
dc.identifier.other ORCID: /0000-0003-4172-3128/work/63686431
dc.identifier.uri http://hdl.handle.net/10138/165644
dc.description.abstract The coincidental evolution hypothesis predicts that traits connected to bacterial pathogenicity could be indirectly selected outside the host as a correlated response to abiotic environmental conditions or different biotic species interactions. To investigate this, an opportunistic bacterial pathogen, Serratia marcescens, was cultured in the absence and presence of the lytic bacteriophage PPV (Podoviridae) at 25°C and 37°C for four weeks (N = 5). At the end, we measured changes in bacterial phage-resistance and potential virulence traits, and determined the pathogenicity of all bacterial selection lines in the Parasemia plantaginis insect model in vivo. Selection at 37°C increased bacterial motility and pathogenicity but only in the absence of phages. Exposure to phages increased the phage-resistance of bacteria, and this was costly in terms of decreased maximum population size in the absence of phages. However, this small-magnitude growth cost was not greater with bacteria that had evolved in high temperature regime, and no trade-off was found between phage-resistance and growth rate. As a result, phages constrained the evolution of a temperature-mediated increase in bacterial pathogenicity presumably by preferably infecting the highly motile and virulent bacteria. In more general perspective, our results suggest that the traits connected to bacterial pathogenicity could be indirectly selected as a correlated response by abiotic and biotic factors in environmental reservoirs. en
dc.format.extent 7
dc.language.iso eng
dc.relation.ispartof PLoS One
dc.rights en
dc.subject 1183 Plant biology, microbiology, virology en
dc.title High temperature and bacteriophages can indirectly select for bacterial pathogenicity in environmental reservoirs en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.1371/journal.pone.0017651
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/publishedVersion
dc.contributor.pbl

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