Femoral Bone Marrow Insulin Sensitivity Is Increased by Resistance Training in Elderly Female Offspring of Overweight and Obese Mothers

Show full item record



Permalink

http://hdl.handle.net/10138/167999

Citation

Huovinen , V , Bucci , M , Lipponen , H , Kiviranta , R , Sandboge , S , Raiko , J , Koskinen , S , Koskensalo , K , Eriksson , J G , Parkkola , R , Iozzo , P & Nuutila , P 2016 , ' Femoral Bone Marrow Insulin Sensitivity Is Increased by Resistance Training in Elderly Female Offspring of Overweight and Obese Mothers ' PLoS One , vol. 11 , no. 9 , 0163723 . DOI: 10.1371/journal.pone.0163723

Title: Femoral Bone Marrow Insulin Sensitivity Is Increased by Resistance Training in Elderly Female Offspring of Overweight and Obese Mothers
Author: Huovinen, Ville; Bucci, Marco; Lipponen, Heta; Kiviranta, Riku; Sandboge, Samuel; Raiko, Juho; Koskinen, Suvi; Koskensalo, Kalle; Eriksson, Johan G.; Parkkola, Riitta; Iozzo, Patricia; Nuutila, Pirjo
Contributor: University of Helsinki, Johan Eriksson / Principal Investigator
Date: 2016-09-26
Language: eng
Number of pages: 14
Belongs to series: PLoS One
ISSN: 1932-6203
URI: http://hdl.handle.net/10138/167999
Abstract: Bone marrow insulin sensitivity may be an important factor for bone health in addition to bone mineral density especially in insulin resistant conditions. First we aimed to study if prenatal maternal obesity plays a role in determining bone marrow insulin sensitivity in elderly female offspring. Secondly we studied if a four-month individualized resistance training intervention increases bone marrow insulin sensitivity in elderly female offspring and whether this possible positive outcome is regulated by the offspring's mother's obesity status. 37 frail elderly females (mean age 71.9 +/- 3.1 years) of which 20 were offspring of lean/normal-weight mothers (OLM, maternal BMI = 28.1 kg/m(2)) were studied before and after a four-month individualized resistance training intervention. Nine age-and sex-matched non-frail controls (maternal BMI
Subject: ADIPOSE-TISSUE
SKELETAL-MUSCLE
GLUCOSE-UPTAKE
MATERNAL OBESITY
MINERAL DENSITY
MR SPECTROSCOPY
OLDER-ADULTS
FAT-CONTENT
IN-VIVO
SECRETION
3121 Internal medicine
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
asset.pdf 1.273Mb PDF View/Open

This item appears in the following Collection(s)

Show full item record