Randomized clinical trial comparing surgery, endovenous laser ablation and ultrasound-guided foam sclerotherapy for the treatment of great saphenous varicose veins

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dc.contributor University of Helsinki, Clinicum en
dc.contributor University of Helsinki, Verisuonikirurgian yksikkö en
dc.contributor University of Helsinki, Clinicum en
dc.contributor University of Helsinki, Verisuonikirurgian yksikkö en
dc.contributor University of Helsinki, Verisuonikirurgian yksikkö en
dc.contributor University of Helsinki, Verisuonikirurgian yksikkö en
dc.contributor.author Venermo, Maarit
dc.contributor.author Saarinen, J.
dc.contributor.author Eskelinen, Elina
dc.contributor.author Vähäaho, Sari M
dc.contributor.author Saarinen, Eva
dc.contributor.author Railo, Mikael
dc.contributor.author Uurto, I.
dc.contributor.author Salenius, J.
dc.contributor.author Albäck, Anders
dc.contributor.author Finnish Venous Study Collaborators
dc.date.accessioned 2016-11-07T07:25:02Z
dc.date.available 2016-11-07T07:25:02Z
dc.date.issued 2016-10
dc.identifier.citation Venermo , M , Saarinen , J , Eskelinen , E , Vähäaho , S M , Saarinen , E , Railo , M , Uurto , I , Salenius , J , Albäck , A & Finnish Venous Study Collaborators 2016 , ' Randomized clinical trial comparing surgery, endovenous laser ablation and ultrasound-guided foam sclerotherapy for the treatment of great saphenous varicose veins ' , British Journal of Surgery , vol. 103 , no. 11 , pp. 1438-1444 . https://doi.org/10.1002/bjs.10260 en
dc.identifier.issn 0007-1323
dc.identifier.other PURE: 71098087
dc.identifier.other PURE UUID: 1f76bb52-4b2f-4144-9606-c087f2de564b
dc.identifier.other WOS: 000384671500005
dc.identifier.other Scopus: 84988647855
dc.identifier.uri http://hdl.handle.net/10138/168615
dc.description.abstract BackgroundEndovenous ablation techniques and ultrasound-guided foam sclerotherapy (UGFS) have largely replaced open surgery for treatment of great saphenous varicose veins. This was a randomized trial to compare the effect of surgery, endovenous laser ablation (EVLA) (with phlebectomies) and UGFS on quality of life and the occlusion rate of the great saphenous vein (GSV) 12months after surgery. MethodsPatients with symptomatic, uncomplicated varicose veins (CEAP class C2-C4) were examined at baseline, 1month and 1year. Before discharge and at 1week, patients reported a pain score on a visual analogue scale. Preoperative and 1-year assessments included duplex ultrasound imaging and the Aberdeen Varicose Vein Severity Score (AVVSS). ResultsThe study included 214 patients: 65 had surgery, 73 had EVLA and 76 had UGFS. At 1year, the GSV was occluded or absent in 59 (97 per cent) of 61 patients after surgery, 71 (97 per cent) of 73 after EVLA and 37 (51 per cent) of 72 after UGFS (P <0001). The AVVSS improved significantly in comparison with preoperative values in all groups, with no significant differences between them. Perioperative pain was significantly reduced and sick leave shorter after UGFS (mean 1day) than after EVLA (8days) and surgery (12days). ConclusionIn comparison with open surgery and EVLA, UGFS resulted in equivalent improvement in quality of life but significantly higher residual GSV reflux at 12-month follow-up. Foam less effective en
dc.format.extent 7
dc.language.iso eng
dc.relation.ispartof British Journal of Surgery
dc.rights en
dc.subject CONVENTIONAL SURGERY en
dc.subject OBLITERATION en
dc.subject LIGATION en
dc.subject 3126 Surgery, anesthesiology, intensive care, radiology en
dc.title Randomized clinical trial comparing surgery, endovenous laser ablation and ultrasound-guided foam sclerotherapy for the treatment of great saphenous varicose veins en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.1002/bjs.10260
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/publishedVersion
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