Articles from TUHAT CRIS


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  • Ranta, Mette; Kruskopf, Milla; Kortesalmi, Marilla; Kalmi, Panu; Lonka, Kirsti (2022)
    The aim of this study was to examine entrepreneurship in the context of future Finnish teachers' readiness to teach 21st century (broad-based) competencies. Teachers' self-efficacy in teaching entrepreneurial skills and financial matters is vital for their pupils to actively participate and flourish in future society. The study utilized survey data of future teachers' expectancy-values in teaching seven broad-based competencies of the current national curriculum and their financial literacy. Future teachers expressed high interest in all competencies but reported the least self-efficacy and highest cost in teaching ICT as well as working life and entrepreneurship competencies. Teaching self-efficacy (TSE) in entrepreneurial competencies was predicted by subjective evaluations of financial capability and TSE in consumer skills. Teaching STEM subjects as well as male gender were related to better objective financial knowledge. We discuss the implications of observed financial capability, lack in self-efficacy, and high experienced cost of teaching these competencies. Support for future teachers' readiness to teach working life skills, entrepreneurship, and financial literacy through phenomenon-based school subject collaboration, formal teacher training, and digital applications are emphasized.
  • Ma, Li; Zhang, Ying; Lin, Zhuohui; Zhou, Ying; Yan, Chao; Zhang, Yusheng; Zhou, Wenshuo; Ma, Wei; Hua, Chenjie; Li, Xiaoxiao; Deng, Chenjuan; Qi, Yu; Dada, Lubna; Li, Hongyan; Bianchi, Federico; Petäjä, Tuukka; Kangasluoma, Juha; Jiang, Jingkun; Liu, Sijin; Hussein, Tareq; Kulmala, Markku; Liu, Yongchun (2022)
    Ultrafine particles (UFPs) usually explosive growth during new particle formation (NPF) events. However, the risk of exposure to UFPs on NPF days has been ignored due to the prevalence of mass-based air quality standards. In this study, the daily deposited doses, i.e., the daily deposited particle number dose (D-PNd), mass dose (D-PMd), and surface area dose (D-PSd), of ambient particles in the human respiratory tract in Beijing were evaluated based on the particle number size distribution (3 nm-10 mu m) from June 2018 to May 2019 utilizing a Multiple-Path Particle Dosimetry Model (MPPD) after the hygroscopic growth of particles in the respiratory tract had been accounted for. Our observations showed a high frequency (72.6%) of NPF on excellent air quality days, with daily mean PM2.5 concentrations less than 35 mu g m(-3). The daily D-PNd on excellent air quality days was com-parable with that on polluted days, although the D-PMd on excellent air quality days was as low as 15.6% of that on polluted days. The D-PNd on NPF days was similar to 1.3 times that on non-NPF days. The D-PNd in respiratory tract regions decreased in the order: tracheobronchial (TB) > pulmonary (PUL) > extrathoracic (ET) on NPF days, while it was PUL > TB > ET on non-NPF days. The number of deposited nucleation mode particles, which were deposited mainly in the TB region (45%), was 2 times higher on NPF days than that on non-NPF days. Our results demonstrated that the deposition potential due to UFPs in terms of particle number concentrations is high in Beijing regardless of the aerosol mass concentration. More toxicological studies related to UFPs on NPF days, especially those targeting tracheobronchial and pulmonary impairment, are required in the future.
  • Tšernova, Žanna; Kulmala, Meri (2021)
  • Sigfrids, Fanny Jansson; Groop, Per-Henrik; Harjutsalo, Valma (2022)
    Background The incidence and temporal trends of moderate and severe albuminuria during recent decades are poorly described in type 1 diabetes. We aimed to assess diabetes duration-specific incidence rates, cumulative incidence, and secular trends of albuminuria in type 1 diabetes in Finland. Methods We conducted a population-based, retrospective cohort study of a stratified random sample (n=1500) of all individuals diagnosed with type 1 diabetes before age 15 years during 1970-99 in Finland. The sampling frame was the database of the Finnish Institute for Health and Welfare. Individuals with an atypical clinical course, presentation of non-diabetic kidney disease, insufficient albumin excretion rate measurements, or unavailable medical records were excluded (final sample n=1430). Study participants were followed up until death, the event of interest (moderate or severe albuminuria or kidney failure), or the most recent event-free date. Medical records retrieved up to Dec 31, 2020 were systematically reviewed for albuminuria determinations. Moderate and severe albuminuria were categorised on the basis of international reference limits (two of three consecutive urine samples). Kidney failure was defined as dialysis treatment or kidney transplant. Cohorts defined by calendar year of diabetes diagnosis (1970-79, 1980-89, and 1990-99) were assessed. Patterns of duration-specific incidences were evaluated by fitting generalised additive models to the data, which were split into multiple observations of half-year duration. Cumulative incidences were calculated with Kaplan-Meier analysis. In analyses with kidney failure as the endpoint, competing risk for mortality was incorporated. Findings In our stratified random sample, 462 individuals were diagnosed with diabetes in 1970-79, 481 were diagnosed in 1980-89, and 487 were diagnosed in 1990-99. The incidence rate pattern of severe albuminuria changed over time; a peak at 15-19 years since diabetes onset in the 1970-79 cohort was not replicated in those diagnosed later. In the combined 1980-99 diagnosis-year cohorts, the incidence rate rose during the first 14 years after diabetes onset, after which it levelled off to a plateau. Between the 1970-79 and 1980-89 diabetes diagnosis cohorts, the cumulative incidence of severe albuminuria had approximately halved (hazard ratio [HR] 0.55 [95% CI 0.42-0.72] with the 1970-79 cohort as reference, p Interpretation Our analyses show that the cumulative incidence of severe albuminuria has decreased between 1970-79 and 1980-99; however, whether this decrease solely denotes a delay in albuminuria, or also a true prevention of albuminuria, needs to be investigated further. Nevertheless, diabetic kidney disease remains a significant complication of type 1 diabetes. Due to the robust association of diabetic kidney disease with premature mortality, novel therapies to improve prognosis are needed. Copyright (C) 2022 Elsevier Ltd. All rights reserved.
  • Frog, Mr. (Kalevala Society, 2021)
    Folklore Fellows' Communications
  • Frog, Mr.; Ahola, Joonas (Kalevala Society, 2021)
    Folklore Fellows' Communications
  • Ao, Bo; He, Fei; Lv, Jing; Tu, Junming; Tan, Zheng; Jiang, Honglin; Shi, Xiaoshan; Li, Jingjing; Hou, Jianjun; Hu, Yuanliang; Xia, Xian (2022)
    Tellurite [Te(IV)] is a high-toxicity metalloid. In this study, a fungus with high Te(IV) resistance was isolated. Strain AB1 could efficiently reduce highly toxic Te(IV) to less toxic Te(0). The reduced products formed rod-shaped biogenetic Te(0) nanoparticles (Bio-TeNPs) intracellularly. Further TEM-element mapping, FTIR, and XPS analysis showed that the extracted Bio-TeNPs ranged from 100 to 500 nm and consisted of Te(0), proteins, lipids, aromatic compounds, and carbohydrates. Moreover, Bio-TeNPs exhibited excellent antibacterial ability against Shigella dysenteriae, Escherichia coli, Enterobacter sakazakii, and Salmonella typhimurium according to inhibition zone tests. Further growth and live/dead staining experiments showed that E. coli and S. typhimurium were significantly inhibited by Bio-TeNPs, and cells were broken or shriveled after treatment with Bio-TeNPs based on SEM observation. Additionally, the antioxidant and cytotoxicity tests showed that the Bio-TeNPs exhibited excellent antioxidant capacity with no cytotoxicity. All these results suggested that strain AB1 showed great potential in bioremediation and Bio-TeNPs were excellent antibacterial nanomaterials with no cytotoxicity.
  • The ALICE collaboration; Acharya, S.; Adamova, D.; Huhta, Laura Maria; Kim, D. J.; Krizek, F.; Molander, Mikael Andreas; Novitzky, Norbert; Onnerstad, A.; Parkkila, J. E.; Rytkönen, Heidi Maria; Räsänen, Sami; Saarimäki, Oskari Antti Matti; Slupecki, M.; Trzaska, W. H. (2022)
  • Ahola, Joonas; Frog, Mr. (Kalevala Society, 2021)
    Folklore Fellows' Communications
  • Vuorio, Alpo; Ramaswami, Uma; Holven, Kirsten B. (2022)
  • van Eijnatten, Maureen; Wolff, Jan; Pauwels, Ruben; Karhu, Kalle; Hietanen, Ari; Sarkissian, Henry der; Koivisto, Juha H. (2022)
    Objective: Cone beam computed tomography (CBCT) images are being increasingly used to acquire three- dimensional (3D) models of the skull for additive manufacturing purposes. However, the accuracy of such models remains a challenge, especially in the orbital area. The aim of this study is to assess the impact of four different CBCT imaging positions on the accuracy of the resulting 3D models in the orbital area. Methods: An anthropomorphic head phantom was manufactured by submerging a dry human skull in silicon to mimic the soft tissue attenuation and scattering properties of the human head. The phantom was scanned on a ProMax 3D MAX CBCT scanner using 90 and 120 kV for four different field of view positions: standard; elevated; backwards tilted; and forward tilted. All CBCT images were subsequently converted into 3D models and geometrically compared with a "gold- standard" optical scan of the dry skull. Results: Mean absolute deviations of the 3D models ranged between 0.15 +/- 0.11 mm and 0.56 +/- 0.28 mm. The elevated imaging position in combination with 120 kV tube voltage resulted in an improved representation of the orbital walls in the resulting 3D model without compromising the accuracy. Conclusions: Head positioning during CBCT imaging can influence the accuracy of the resulting 3D model. The accuracy of such models may be improved by positioning the region of interest (e.g. the orbital area) in the focal plane (Figure 2a) of the CBCT X- ray beam.
  • Alho, Kimmo; Moisala, Mona; Salmela-Aro, Katariina (2022)
    The increasing use of digital technology among adolescents and young adults has led to concerns about possible detrimental effects on cognitive and brain functions. Indeed, as reviewed here, according to behavioral and brain-imaging studies, excessive media multitasking (i.e., using different digital media in parallel) may lead to enhanced distractibility and problems in maintaining attention. However, frequent video gaming may be beneficial for the development of working memory, task switching, and attention skills. All these cognitive skills depend on executive cognitive functions. Stitt scant but gradually cumulating brain-imaging results suggest that the negative effects of frequent media multitasking and the positive effects of frequent video gaming on cognitive skills in adolescents and young adults are mediated by effects on the frontal lobes, implicated in executive cognitive functions and still developing even through early adulthood.
  • Roberts, Nicholas L. S.; Johnson, Emily K.; Zeng, Scott M.; Hamilton, Erin B.; Abdoli, Amir; Alahdab, Fares; Alipour, Vahid; Ancuceanu, Robert; Andrei, Catalina Liliana; Anvari, Davood; Arabloo, Jalal; Ausloos, Marcel; Awedew, Atalel Fentahun; Badiye, Ashish D.; Bakkannavar, Shankar M.; Bhalla, Ashish; Bhardwaj, Nikha; Bhardwaj, Pankaj; Bhaumik, Soumyadeep; Bijani, Ali; Boloor, Archith; Cai, Tianji; Carvalho, Felix; Chu, Dinh-Toi; Couto, Rosa A. S.; Dai, Xiaochen; Desta, Abebaw Alemayehu; Do, Hoa Thi; Earl, Lucas; Eftekhari, Aziz; Esmaeilzadeh, Firooz; Farzadfar, Farshad; Fernandes, Eduarda; Filip, Irina; Foroutan, Masoud; Franklin, Richard Charles; Gaidhane, Abhay Motiramji; Gebregiorgis, Birhan Gebresillassie; Gebremichael, Berhe; Ghashghaee, Ahmad; Golechha, Mahaveer; Hamidi, Samer; Haque, Syed Emdadul; Hayat, Khezar; Herteliu, Claudiu; Ilesanmi, Olayinka Stephen; Islam, M. Mofizul; Jagnoor, Jagnoor; Kanchan, Tanuj; Kapoor, Neeti; Khan, Ejaz Ahmad; Khatib, Mahalaqua Nazli; Khundkar, Roba; Krishan, Kewal; Kumar, G. Anil; Kumar, Nithin; Landires, Ivan; Lim, Stephen S.; Madadin, Mohammed; Maled, Venkatesh; Manafi, Navid; Marczak, Laurie B.; Menezes, Ritesh G.; Meretoja, Tuomo J.; Miller, Ted R.; Mohammadian-Hafshejani, Abdollah; Mokdad, Ali H.; Monteiro, Francis N. P.; Moradi, Maryam; Nayak, Vinod C.; Nguyen, Cuong Tat; Nguyen, Huong Lan Thi; Nunez-Samudio, Virginia; Ostroff, Samuel M.; Padubidri, Jagadish Rao; Pham, Hai Quang; Pinheiro, Marina; Pirestani, Majid; Syed, Zahiruddin Quazi; Rabiee, Navid; Radfar, Amir; Rahimi-Movaghar, Vafa; Rao, Sowmya J.; Rastogi, Prateek; Rawaf, David Laith; Rawaf, Salman; Reiner, Robert C.; Sahebkar, Amirhossein; Samy, Abdallah M.; Sawhney, Monika; Schwebel, David C.; Senthilkumaran, Subramanian; Shaikh, Masood Ali; Skryabin, Valentin Yurievich; Skryabina, Anna Aleksandrovna; Soheili, Amin; Stokes, Mark A.; Thapar, Rekha; Tovani-Palone, Marcos Roberto; Tran, Bach Xuan; Travillian, Ravensara S.; Velazquez, Diana Zuleika; Zhang, Zhi-Jiang; Naghavi, Mohsen; Dandona, Rakhi; Dandona, Lalit; James, Spencer L.; Pigott, David M.; Murray, Christopher J. L.; Hay, Simon; Vos, Theo; Ong, Kanyin Liane (2022)
    Snakebite envenoming is an important cause of preventable death. The World Health Organization (WHO) set a goal to halve snakebite mortality by 2030. We used verbal autopsy and vital registration data to model the proportion of venomous animal deaths due to snakes by location, age, year, and sex, and applied these proportions to venomous animal contact mortality estimates from the Global Burden of Disease 2019 study. In 2019, 63,400 people (95% uncertainty interval 38,900-78,600) died globally from snakebites, which was equal to an age-standardized mortality rate (ASMR) of 0.8 deaths (0.5-1.0) per 100,000 and represents a 36% (2-49) decrease in ASMR since 1990. India had the greatest number of deaths in 2019, equal to an ASMR of 4.0 per 100,000 (2.3-5.0). We forecast mortality will continue to decline, but not sufficiently to meet WHO's goals. Improved data collection should be prioritized to help target interventions, improve burden estimation, and monitor progress.
  • The Reims Heart Team; Olivier, Maud-Emmanuelle; Di Cesare, Alessandro; Poncet, Anne; Biancari, Fausto; Ruggieri, Vito Giovanni (2022)
    Objectives: To compare the outcomes after transcatheter aortic valve replacement (TAVR) through a transfemoral (TF) and transcarotid (TC) access at our institution.Methods: From January 2014 to January 2020, 62 TC-TAVR and 449 TF-TAVR were performed using 2 prosthesis devices (Edwards SAPIEN 3, n = 369; Medtronic Evo-lut R, n = 142). Propensity score matching was used to adjust for imbalance in the baseline characteristics of the study groups.Results: Propensity score matching provided 62 matched pairs with comparable operative risk (mean European System for Cardiac Operative Risk Evaluation II, TC-TAVR 7.6% vs TF-TAVR 6.6%, P = .17). Thirty-day mortality (4.8% vs 3.2%, P = 1.00) and 2-year mortality (11.3% vs 12.9%, P = .64) after TC-TAVR were com-parable with TF-TAVR. Strokes were numerically more frequent after TC-TAVR compared with TF-TAVR (3.2% vs 0%, P = .23), but the difference did not reach statistical significance. TF-TAVR was associated with a significantly greater risk of permanent pacemaker implantation (29.0% vs 12.9%, P = .04) compared with TC-TAVR. Other complications were not frequent and were similarly distributed be-tween the matched groups.Conclusions: TC access for TAVR was associated with satisfactory results compared to the femoral access. TC-TAVR could be considered a valid and safe alternative to TF-TAVR when femoral access is contraindicated. (JTCVS Techniques 2022;15:46-53)
  • Watson, Timothy; Tervala, Juha (Australian National University, 2022)
    Australian National University, CAMA working paper series
  • OBSERVANT II Research Group; Fraccaro, Chiara; Tarantini, Giuseppe; Rosato, Stefano; Biancari, Fausto; D'Errigo, Paola (2022)
  • Vainio, Olli-Pekka (Suomalainen teologinen kirjallisuusseura, 2021)
    Suomalaisen teologisen kirjallisuusseuran julkaisuja
  • Saarinen, Risto (Suomalainen teologinen kirjallisuusseura, 2021)
    Suomalaisen Teologisen Kirjallisuusseuran julkaisuja
  • Huttunen, Niko (Suomalainen teologinen kirjallisuusseura, 2021)
    Suomalaisen Teologisen Kirjallisuusseuran julkaisuja

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