Left Ventricular Geometry and Risk of Sudden Cardiac Arrest in Patients With Severely Reduced Ejection Fraction

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http://hdl.handle.net/10138/172744

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Phan , D , Aro , A L , Reinier , K , Teodorescu , C , Uy-Evanado , A , Gunson , K , Jui , J & Chugh , S S 2016 , ' Left Ventricular Geometry and Risk of Sudden Cardiac Arrest in Patients With Severely Reduced Ejection Fraction ' Journal of the American Heart Association , vol. 5 , no. 8 , 003715 . DOI: 10.1161/JAHA.116.003715

Title: Left Ventricular Geometry and Risk of Sudden Cardiac Arrest in Patients With Severely Reduced Ejection Fraction
Author: Phan, Derek; Aro, Aapo L.; Reinier, Kyndaron; Teodorescu, Carmen; Uy-Evanado, Audrey; Gunson, Karen; Jui, Jonathan; Chugh, Sumeet S.
Contributor: University of Helsinki, Department of Medicine
Date: 2016-08
Language: eng
Number of pages: 10
Belongs to series: Journal of the American Heart Association
ISSN: 2047-9980
URI: http://hdl.handle.net/10138/172744
Abstract: Background-Recent reports indicate that specific left ventricular (LV) geometric patterns predict recurrent ventricular arrhythmias in patients with implantable cardioverter-defibrillators and reduced left ventricular ejection fraction (LVEF). However, this relationship has not been evaluated among patients at risk of sudden cardiac arrest (SCA) in the general population. Methods and Results-Adult SCA cases from the Oregon Sudden Unexpected Death Study were compared with geographic controls with no prior history of SCA. Archived echocardiograms performed closest and prior to the SCA event were reviewed. LV geometry was defined as normal (normal LV mass index [LVMI] and relative wall thickness [RWT]), concentric remodeling (normal LVMI and increased RWT), concentric hypertrophy (increased LVMI and RWT), or eccentric hypertrophy (increased LVMI and normal RWT). Analysis was restricted to those with LVEF Conclusions-Eccentric LV hypertrophy was independently associated with increased risk of SCA in subjects with EF
Subject: eccentric hypertrophy
left ventricular geometry
sudden cardiac arrest
IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR
CORONARY-ARTERY-DISEASE
MYOCARDIAL-INFARCTION
PROGNOSTIC IMPLICATIONS
HYPERTENSIVE PATIENTS
HEART-ASSOCIATION
WALL THICKNESS
MASS
DEATH
MORTALITY
3121 Internal medicine
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