Snake Genome Sequencing : Results and Future Prospects

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http://hdl.handle.net/10138/174343

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Kerkkamp , H M I , Kini , R M , Pospelov , A S , Vonk , F J , Henkel , C V & Richardson , M K 2016 , ' Snake Genome Sequencing : Results and Future Prospects ' , Toxins , vol. 8 , no. 12 . https://doi.org/10.3390/toxins8120360

Title: Snake Genome Sequencing : Results and Future Prospects
Author: Kerkkamp, Harald M. I.; Kini, R. Manjunatha; Pospelov, Alexey S.; Vonk, Freek J.; Henkel, Christiaan V.; Richardson, Michael K.
Contributor: University of Helsinki, Biosciences
Date: 2016-12
Language: eng
Number of pages: 15
Belongs to series: Toxins
ISSN: 2072-6651
URI: http://hdl.handle.net/10138/174343
Abstract: Snake genome sequencing is in its infancy-very much behind the progress made in sequencing the genomes of humans, model organisms and pathogens relevant to biomedical research, and agricultural species. We provide here an overview of some of the snake genome projects in progress, and discuss the biological findings, with special emphasis on toxinology, from the small number of draft snake genomes already published. We discuss the future of snake genomics, pointing out that new sequencing technologies will help overcome the problem of repetitive sequences in assembling snake genomes. Genome sequences are also likely to be valuable in examining the clustering of toxin genes on the chromosomes, in designing recombinant antivenoms and in studying the epigenetic regulation of toxin gene expression.
Subject: snake
genome
genomics
king cobra
reptile
Malayan pit viper
PROTEIN-CODING GENES
VENOM SYSTEM
ADAPTIVE EVOLUTION
BOTHROPS-JARARACA
TOXIN RESISTANCE
3-FINGER TOXINS
MOLECULAR-BASIS
CHICKEN GENOME
ORIGIN
DUPLICATION
1181 Ecology, evolutionary biology
1184 Genetics, developmental biology, physiology
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