Low Ambient Temperature and Intracerebral Hemorrhage : The INTERACT2 Study

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Zheng , D , Arima , H , Sato , S , Gasparrini , A , Heeley , E , Delcourt , C , Lo , S , Huang , Y , Wang , J , Stapf , C , Robinson , T , Lavados , P , Chalmers , J , Anderson , C S , INTERACT2 Investigators , Scheperjans , F & Kaste , M 2016 , ' Low Ambient Temperature and Intracerebral Hemorrhage : The INTERACT2 Study ' , PLoS One , vol. 11 , no. 2 , 0149040 . https://doi.org/10.1371/journal.pone.0149040

Title: Low Ambient Temperature and Intracerebral Hemorrhage : The INTERACT2 Study
Author: Zheng, Danni; Arima, Hisatomi; Sato, Shoichiro; Gasparrini, Antonio; Heeley, Emma; Delcourt, Candice; Lo, Serigne; Huang, Yining; Wang, Jiguang; Stapf, Christian; Robinson, Thompson; Lavados, Pablo; Chalmers, John; Anderson, Craig S.; INTERACT2 Investigators; Scheperjans, Filip; Kaste, Markku
Contributor: University of Helsinki, Neurologian yksikkö
University of Helsinki, Neurologian yksikkö
Date: 2016-02-09
Language: eng
Number of pages: 14
Belongs to series: PLoS One
ISSN: 1932-6203
URI: http://hdl.handle.net/10138/174900
Abstract: Background Rates of acute intracerebral hemorrhage (ICH) increase in winter months but the magnitude of risk is unknown. We aimed to quantify the association of ambient temperature with the risk of ICH in the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT2) participants on an hourly timescale. Methods INTERACT2 was an international, open, blinded endpoint, randomized controlled trial of patients with spontaneous ICH ( Results were presented as overall cumulative odds ratios (ORs) and 95% CI. Results Low ambient temperature ( Conclusions Exposure to low ambient temperature within several hours increases the risk of ICH.
Subject: REFERENT SELECTION-STRATEGIES
BLOOD-PRESSURE
CASE-CROSSOVER
HOSPITAL ADMISSIONS
ISCHEMIC-STROKE
HEART-DISEASE
MORTALITY
MULTICENTER
PATTERNS
EXPOSURE
3124 Neurology and psychiatry
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