The Relationship between Thyroid Function and Depressive Symptoms—the FIN-D2D Population-Based Study

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http://hdl.handle.net/10138/176223

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Saltevo , J , Kautiainen , H , Mäntyselkä , P , Jula , A , Keinänen-Kiukaanniemi , S , Korpi-Hyövälti , E , Oksa , H , Saaristo , T & Vanhala , M 2015 , ' The Relationship between Thyroid Function and Depressive Symptoms—the FIN-D2D Population-Based Study ' , Clinical Medicine Insights: Endocrinology and Diabetes , vol. 8 , pp. 29-33 . https://doi.org/10.4137/CMED.S24111

Titel: The Relationship between Thyroid Function and Depressive Symptoms—the FIN-D2D Population-Based Study
Författare: Saltevo, Juha; Kautiainen, Hannu; Mäntyselkä, Pekka; Jula, Antti; Keinänen-Kiukaanniemi, Sirkka; Korpi-Hyövälti, Eeva; Oksa, Heikki; Saaristo, Timo; Vanhala, Mauno
Upphovmannens organisation: Department of General Practice and Primary Health Care
Datum: 2015-04-01
Språk: eng
Sidantal: 5
Tillhör serie: Clinical Medicine Insights: Endocrinology and Diabetes
ISSN: 1179-5514
DOI: https://doi.org/10.4137/CMED.S24111
Permanenta länken (URI): http://hdl.handle.net/10138/176223
Abstrakt: The association between thyroid function and depression is controversial. Both conditions express many similar symptoms, but the studies done give conflicting results. This study draws on a random, population-based sample of 4500 subjects aged 45–75 years old from Finland. The basic clinical study was done in 2007 for 1396 men and 1500 women (64% participation rate). Thyroid stimulating hormone (TSH), free thyroxine (F-T4), and free triiodothyronine (F-T3) were measured in 2013 from frozen samples. The 21-item Beck Depression Inventory (BDI-21) was applied to assess depressive symptoms (score ≥10 points). The prevalence of depressive symptoms was 17.5% in women and 12.5% in men. In women, the mean levels of TSH, F-T4, and F-T3 without depressive symptoms vs. with the presence of depressive symptoms were 1.92/1.97 mU/L, 13.1/13.1 pmol/L, and 3.91/3.87 pmol/L (NS), respectively. In men, the levels were 1.87/1.94 mU/L, 13.5/13.7 pmol/L, and 4.18/4.12 pmol/L (NS), respectively. In multiple regression analysis, TSH had no relationship to BDI-21 total score. We found no association between depressive symptoms and thyroid values.
Subject: 3142 Public health care science, environmental and occupational health
Referentgranskad: Ja
Licens: cc_by_nc
Användningsbegränsning: openAccess
Parallelpublicerad version: publishedVersion


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