The Relationship between Thyroid Function and Depressive Symptoms—the FIN-D2D Population-Based Study

Show simple item record

dc.contributor.author Saltevo, Juha
dc.contributor.author Kautiainen, Hannu
dc.contributor.author Mäntyselkä, Pekka
dc.contributor.author Jula, Antti
dc.contributor.author Keinänen-Kiukaanniemi, Sirkka
dc.contributor.author Korpi-Hyövälti, Eeva
dc.contributor.author Oksa, Heikki
dc.contributor.author Saaristo, Timo
dc.contributor.author Vanhala, Mauno
dc.date.accessioned 2017-02-27T10:23:01Z
dc.date.available 2017-02-27T10:23:01Z
dc.date.issued 2015-04-01
dc.identifier.citation Saltevo , J , Kautiainen , H , Mäntyselkä , P , Jula , A , Keinänen-Kiukaanniemi , S , Korpi-Hyövälti , E , Oksa , H , Saaristo , T & Vanhala , M 2015 , ' The Relationship between Thyroid Function and Depressive Symptoms—the FIN-D2D Population-Based Study ' , Clinical Medicine Insights: Endocrinology and Diabetes , vol. 8 , pp. 29-33 . https://doi.org/10.4137/CMED.S24111
dc.identifier.other PURE: 80538631
dc.identifier.other PURE UUID: 773d6544-0b78-4d6b-84c2-d2453a312803
dc.identifier.other Bibtex: urn:87afbdda7c73aa2206572c28b8be181f
dc.identifier.other Scopus: 84934940793
dc.identifier.uri http://hdl.handle.net/10138/176223
dc.description.abstract The association between thyroid function and depression is controversial. Both conditions express many similar symptoms, but the studies done give conflicting results. This study draws on a random, population-based sample of 4500 subjects aged 45–75 years old from Finland. The basic clinical study was done in 2007 for 1396 men and 1500 women (64% participation rate). Thyroid stimulating hormone (TSH), free thyroxine (F-T4), and free triiodothyronine (F-T3) were measured in 2013 from frozen samples. The 21-item Beck Depression Inventory (BDI-21) was applied to assess depressive symptoms (score ≥10 points). The prevalence of depressive symptoms was 17.5% in women and 12.5% in men. In women, the mean levels of TSH, F-T4, and F-T3 without depressive symptoms vs. with the presence of depressive symptoms were 1.92/1.97 mU/L, 13.1/13.1 pmol/L, and 3.91/3.87 pmol/L (NS), respectively. In men, the levels were 1.87/1.94 mU/L, 13.5/13.7 pmol/L, and 4.18/4.12 pmol/L (NS), respectively. In multiple regression analysis, TSH had no relationship to BDI-21 total score. We found no association between depressive symptoms and thyroid values. en
dc.format.extent 5
dc.language.iso eng
dc.relation.ispartof Clinical Medicine Insights: Endocrinology and Diabetes
dc.rights cc_by_nc
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject 3142 Public health care science, environmental and occupational health
dc.title The Relationship between Thyroid Function and Depressive Symptoms—the FIN-D2D Population-Based Study en
dc.type Article
dc.contributor.organization Department of General Practice and Primary Health Care
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.4137/CMED.S24111
dc.relation.issn 1179-5514
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

Files in this item

Total number of downloads: Loading...

Files Size Format View
f_4782_CMED_The ... ve_Symptomsth.pdf_6410.pdf 785.5Kb PDF View/Open

This item appears in the following Collection(s)

Show simple item record