Cervical artery dissection in patients >= 60 years Often painless, few mechanical triggers

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http://hdl.handle.net/10138/180297

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Traenka , C , Dougoud , D , Simonetti , B G , Metso , T M , Debette , S , Pezzini , A , Kloss , M , Grond-Ginsbach , C , Majersik , J J , Worrall , B B , Leys , D , Baumgartner , R , Caso , V , Bejot , Y , Compter , A , Reiner , P , Thijs , V , Southerland , A M , Bersano , A , Brandt , T , Gensicke , H , Touze , E , Martin , J J , Chabriat , H , Tatlisumak , T , Lyrer , P , Arnold , M & Engelter , S T 2017 , ' Cervical artery dissection in patients >= 60 years Often painless, few mechanical triggers ' , Neurology , vol. 88 , no. 14 , pp. 1313-1320 . https://doi.org/10.1212/WNL.0000000000003788

Title: Cervical artery dissection in patients >= 60 years Often painless, few mechanical triggers
Author: Traenka, Christopher; Dougoud, Daphne; Simonetti, Barbara Goeggel; Metso, Tiina Maria; Debette, Stephanie; Pezzini, Alessandro; Kloss, Manja; Grond-Ginsbach, Caspar; Majersik, Jennifer J.; Worrall, Bradford B.; Leys, Didier; Baumgartner, Ralf; Caso, Valeria; Bejot, Yannick; Compter, Annette; Reiner, Peggy; Thijs, Vincent; Southerland, Andrew M.; Bersano, Anna; Brandt, Tobias; Gensicke, Henrik; Touze, Emmanuel; Martin, Juan J.; Chabriat, Hugues; Tatlisumak, Turgut; Lyrer, Philippe; Arnold, Marcel; Engelter, Stefan T.
Contributor: University of Helsinki, Neurologian yksikkö
University of Helsinki, Neurologian yksikkö
Date: 2017-04-04
Language: eng
Number of pages: 8
Belongs to series: Neurology
ISSN: 0028-3878
URI: http://hdl.handle.net/10138/180297
Abstract: Objective: In a cohort of patients diagnosed with cervical artery dissection (CeAD), to determine the proportion of patients aged >= 60 years and compare the frequency of characteristics (presenting symptoms, risk factors, and outcome) in patients aged = 60 years. Methods: We combined data from 3 large cohorts of consecutive patients diagnosed with CeAD (i. e., Cervical Artery Dissection and Ischemic Stroke Patients-Plus consortium). We dichotomized cases into 2 groups, age >= 60 and Results: Among 2,391 patients diagnosed with CeAD, we identified 177 patients (7.4%) aged >= 60 years. In this age group, cervical pain (ORadjusted 0.47 [0.33-0.66]), headache (ORadjusted 0.58 [0.42-0.79]), mechanical trigger events (ORadjusted 0.53 [0.36-0.77]), and migraine (ORadjusted 0.58 [0.39-0.85]) were less frequent than in younger patients. In turn, hypercholesterolemia (ORadjusted 1.52 [1.1-2.10]) and hypertension (ORadjusted 3.08 [2.25-4.22]) were more frequent in older patients. Key differences between age groups were confirmed in secondary analyses. In multivariable, adjusted analyses, favorable outcome (i. e., modified Rankin Scale score 0-2) was less frequent in the older age group (ORadjusted 0.45 [0.25, 0.83]). Conclusion: In our study population of patients diagnosed with CeAD, 1 in 14 was aged >= 60 years. In these patients, pain and mechanical triggers might be missing, rendering the diagnosis more challenging and increasing the risk ofmissed CeAD diagnosis in older patients.
Subject: BRAIN-SUPPLYING ARTERIES
ISCHEMIC-STROKE PATIENTS
VASCULAR RISK-FACTORS
VERTEBRAL ARTERY
CAROTID-ARTERY
YOUNG-ADULTS
MIGRAINE
CADISP
PREVALENCE
FEATURES
3124 Neurology and psychiatry
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