Vitamin C and Infections

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Hemilä , H 2017 , ' Vitamin C and Infections ' , Nutrients , vol. 9 , no. 4 , pp. 339 .

Title: Vitamin C and Infections
Author: Hemilä, Harri
Contributor organization: Harri Hemilä / Principal Investigator
Department of Public Health
Date: 2017
Language: eng
Number of pages: 28
Belongs to series: Nutrients
ISSN: 2072-6643
Abstract: In the early literature, vitamin C deficiency was associated with pneumonia. After its identification, a number of studies investigated the effects of vitamin C on diverse infections. A total of 148 animal studies indicated that vitamin C may alleviate or prevent infections caused by bacteria, viruses, and protozoa. The most extensively studied human infection is the common cold. Vitamin C administration does not decrease the average incidence of colds in the general population, yet it halved the number of colds in physically active people. Regularly administered vitamin C has shortened the duration of colds, indicating a biological effect. However, the role of vitamin C in common cold treatment is unclear. Two controlled trials found a statistically significant dose-response, for the duration of common cold symptoms, with up to 6-8 g/day of vitamin C. Thus, the negative findings of some therapeutic common cold studies might be explained by the low doses of 3-4 g/day of vitamin C. Three controlled trials found that vitamin C prevented pneumonia. Two controlled trials found a treatment benefit of vitamin C for pneumonia patients. One controlled trial reported treatment benefits for tetanus patients. The effects of vitamin C against infections should be investigated further.
Subject: 3121 General medicine, internal medicine and other clinical medicine
Vitamin C
Ascorbic Acid
Common Cold
herpes zoster
Respiratory tract infections
3142 Public health care science, environmental and occupational health
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion

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