Poor sleep predicts symptoms of depression and disability retirement due to depression

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http://hdl.handle.net/10138/203420

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Paunio , T , Korhonen , T , Hublin , C , Partinen , M , Harkonmäki , K , Koskenvuo , M & Kaprio , J 2014 , ' Poor sleep predicts symptoms of depression and disability retirement due to depression ' , Journal of Affective Disorders , vol. 172C , pp. 381-389 . https://doi.org/10.1016/j.jad.2014.10.002

Titel: Poor sleep predicts symptoms of depression and disability retirement due to depression
Författare: Paunio, Tiina; Korhonen, Tellervo; Hublin, Christer; Partinen, Markku; Harkonmäki, Karoliina; Koskenvuo, Markku; Kaprio, Jaakko
Medarbetare: University of Helsinki, Clinicum
University of Helsinki, Hjelt Institute (-2014)
University of Helsinki, Helsinki Sleep Clinic, Vitalmed Research Centre, Helsinki
University of Helsinki, Hjelt Institute (-2014)
University of Helsinki, Hjelt Institute (-2014)
University of Helsinki, Hjelt Institute (-2014)
Datum: 2014
Språk: eng
Sidantal: 9
Tillhör serie: Journal of Affective Disorders
ISSN: 0165-0327
Permanenta länken (URI): http://hdl.handle.net/10138/203420
Abstrakt: BACKGROUND: Disturbed sleep is associated with mood disorders. Both depression and insomnia may increase the risk of disability retirement. The longitudinal links among insomnia, depression and work incapacity are poorly known. METHODS: We examined association of self-reported sleep quality with incident symptoms of depression and disability retirement due to depressive disorders in a longitudinal population-based sample of twins (n=12,063 individuals). These adults were categorized by their sleep quality in 1975 and 1981, excluding individuals with depressed mood in 1975/1981. The outcomes were the Beck Depression Inventory (BDItot) and its subscale Negative Attitudes Towards Self (BDINATS) in 1990 as dichotomized measures, and the incidence of disability retirement due to depressive disorder during 1991-2004. RESULTS: Onset of poor sleep between 1975 and 1981 predicted incident depression (BDItot OR=4.5, 95% CI: 2.7-7.4, BDINATS OR=2.0, 95% CI: 1.4-2.7), while persistent poor sleep showed somewhat weaker effects (BDItot; OR=2.5, 95% CI: 1.0-6.0, BDINATS OR=1.9, 95% CI: 1.1-3.3). Among those with few recent stressful life events, onset of poor sleep predicted strongly depression (BDINATS OR=9.5, 95% CI: 3.7-24.2). Likewise onset of poor sleep by 1981 increased the risk of disability retirement due to depression (OR=2.9, 95% CI: 1.8-4.9) with a similar risk among those with persistent poor sleep (OR=2.7, 95% CI: 1.3-5.7). LIMITATIONS: Lack of baseline diagnostic interviews; sleep quality based on self-report. CONCLUSIONS: Poor sleep is of importance in etiology of depression and disability retirement due to depression. This emphasizes the importance of early detection and treatment of sleep disturbances.
Subject: 3142 Public health care science, environmental and occupational health
sleep disorders
cohort studies
sleep
depression
disability
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