Poor sleep predicts symptoms of depression and disability retirement due to depression

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dc.contributor University of Helsinki, Clinicum en
dc.contributor University of Helsinki, Hjelt Institute (-2014) en
dc.contributor University of Helsinki, Helsinki Sleep Clinic, Vitalmed Research Centre, Helsinki en
dc.contributor University of Helsinki, Hjelt Institute (-2014) en
dc.contributor University of Helsinki, Hjelt Institute (-2014) en
dc.contributor University of Helsinki, Hjelt Institute (-2014) en
dc.contributor.author Paunio, Tiina
dc.contributor.author Korhonen, Tellervo
dc.contributor.author Hublin, Christer
dc.contributor.author Partinen, Markku
dc.contributor.author Harkonmäki, Karoliina
dc.contributor.author Koskenvuo, Markku
dc.contributor.author Kaprio, Jaakko
dc.date.accessioned 2017-07-24T13:03:00Z
dc.date.available 2017-07-24T13:03:00Z
dc.date.issued 2014
dc.identifier.citation Paunio , T , Korhonen , T , Hublin , C , Partinen , M , Harkonmäki , K , Koskenvuo , M & Kaprio , J 2014 , ' Poor sleep predicts symptoms of depression and disability retirement due to depression ' , Journal of Affective Disorders , vol. 172C , pp. 381-389 . https://doi.org/10.1016/j.jad.2014.10.002 en
dc.identifier.issn 0165-0327
dc.identifier.other PURE: 45306273
dc.identifier.other PURE UUID: ccbd1e27-797d-47a6-9224-74d75a9400da
dc.identifier.other WOS: 000346643000054
dc.identifier.other Scopus: 84913529841
dc.identifier.other ORCID: /0000-0002-8182-9368/work/29029317
dc.identifier.uri http://hdl.handle.net/10138/203420
dc.description.abstract BACKGROUND: Disturbed sleep is associated with mood disorders. Both depression and insomnia may increase the risk of disability retirement. The longitudinal links among insomnia, depression and work incapacity are poorly known. METHODS: We examined association of self-reported sleep quality with incident symptoms of depression and disability retirement due to depressive disorders in a longitudinal population-based sample of twins (n=12,063 individuals). These adults were categorized by their sleep quality in 1975 and 1981, excluding individuals with depressed mood in 1975/1981. The outcomes were the Beck Depression Inventory (BDItot) and its subscale Negative Attitudes Towards Self (BDINATS) in 1990 as dichotomized measures, and the incidence of disability retirement due to depressive disorder during 1991-2004. RESULTS: Onset of poor sleep between 1975 and 1981 predicted incident depression (BDItot OR=4.5, 95% CI: 2.7-7.4, BDINATS OR=2.0, 95% CI: 1.4-2.7), while persistent poor sleep showed somewhat weaker effects (BDItot; OR=2.5, 95% CI: 1.0-6.0, BDINATS OR=1.9, 95% CI: 1.1-3.3). Among those with few recent stressful life events, onset of poor sleep predicted strongly depression (BDINATS OR=9.5, 95% CI: 3.7-24.2). Likewise onset of poor sleep by 1981 increased the risk of disability retirement due to depression (OR=2.9, 95% CI: 1.8-4.9) with a similar risk among those with persistent poor sleep (OR=2.7, 95% CI: 1.3-5.7). LIMITATIONS: Lack of baseline diagnostic interviews; sleep quality based on self-report. CONCLUSIONS: Poor sleep is of importance in etiology of depression and disability retirement due to depression. This emphasizes the importance of early detection and treatment of sleep disturbances. en
dc.format.extent 9
dc.language.iso eng
dc.relation.ispartof Journal of Affective Disorders
dc.rights en
dc.subject 3142 Public health care science, environmental and occupational health en
dc.subject sleep disorders en
dc.subject cohort studies en
dc.subject sleep en
dc.subject depression en
dc.subject disability en
dc.title Poor sleep predicts symptoms of depression and disability retirement due to depression en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.1016/j.jad.2014.10.002
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/publishedVersion
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