Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1

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Glubb , D M , Maranian , M J , Michailidou , K , Pooley , K A , Meyer , K B , Kar , S , Carlebur , S , O'Reilly , M , Betts , J A , Hillman , K M , Kaufmann , S , Beesley , J , Canisius , S , Hopper , J L , Southey , M C , Tsimiklis , H , Apicella , C , Schmidt , M K , Broeks , A , Hogervorst , F B , van der Schoot , C E , Muir , K , Lophatananon , A , Stewart-Brown , S , Siriwanarangsan , P , Fasching , P A , Ruebner , M , Ekici , A B , Beckmann , M W , Peto , J , Dos-Santos-Silva , I , Fletcher , O , Johnson , N , Pharoah , P D P , Bolla , M K , Wang , Q , Dennis , J , Sawyer , E J , Tomlinson , I , Kerin , M J , Miller , N , Burwinkel , B , Marme , F , Yang , R , Surowy , H , Guenel , P , Nevanlinna , H , Muranen , T A , Aittomäki , K , Blomqvist , C , GENICA Network , KConFab Investigators & Norwegian Breast Canc Study 2015 , ' Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1 ' American Journal of Human Genetics , vol. 96 , no. 1 , pp. 5-20 . DOI: 10.1016/j.ajhg.2014.11.009

Title: Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1
Author: Glubb, Dylan M.; Maranian, Mel J.; Michailidou, Kyriaki; Pooley, Karen A.; Meyer, Kerstin B.; Kar, Siddhartha; Carlebur, Saskia; O'Reilly, Martin; Betts, Joshua A.; Hillman, Kristine M.; Kaufmann, Susanne; Beesley, Jonathan; Canisius, Sander; Hopper, John L.; Southey, Melissa C.; Tsimiklis, Helen; Apicella, Carmel; Schmidt, Marjanka K.; Broeks, Annegien; Hogervorst, Frans B.; van der Schoot, C. Ellen; Muir, Kenneth; Lophatananon, Artitaya; Stewart-Brown, Sarah; Siriwanarangsan, Pornthep; Fasching, Peter A.; Ruebner, Matthias; Ekici, Arif B.; Beckmann, Matthias W.; Peto, Julian; Dos-Santos-Silva, Isabel; Fletcher, Olivia; Johnson, Nichola; Pharoah, Paul D. P.; Bolla, Manjeet K.; Wang, Qin; Dennis, Joe; Sawyer, Elinor J.; Tomlinson, Ian; Kerin, Michael J.; Miller, Nicola; Burwinkel, Barbara; Marme, Frederik; Yang, Rongxi; Surowy, Harald; Guenel, Pascal; Nevanlinna, Heli; Muranen, Taru A.; Aittomäki, Kristiina; Blomqvist, Carl; GENICA Network; KConFab Investigators; Norwegian Breast Canc Study
Contributor: University of Helsinki, Department of Obstetrics and Gynegology
University of Helsinki, Department of Obstetrics and Gynegology
University of Helsinki, Department of Medical and Clinical Genetics
University of Helsinki, Department of Oncology
Date: 2015-01-08
Language: eng
Number of pages: 16
Belongs to series: American Journal of Human Genetics
ISSN: 0002-9297
URI: http://hdl.handle.net/10138/203748
Subject: GENOME-WIDE ASSOCIATION
CYCLIN D1 EXPRESSION
FUNCTIONAL VARIANTS
SUSCEPTIBILITY LOCI
GENES
PROMOTER
ACTIVATION
APOPTOSIS
SUBTYPES
TUMORS
3111 Biomedicine
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