Morbidity and Causes of Death in Patients with Cutaneous T-cell Lymphoma in Finland

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http://hdl.handle.net/10138/211840

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Vakeva , L , Lipsanen , T , Sintonen , H & Ranki , A 2017 , ' Morbidity and Causes of Death in Patients with Cutaneous T-cell Lymphoma in Finland ' , Acta Dermato-Venereologica , vol. 97 , no. 6 , pp. 735-738 . https://doi.org/10.2340/00015555-2629

Title: Morbidity and Causes of Death in Patients with Cutaneous T-cell Lymphoma in Finland
Author: Vakeva, Liisa; Lipsanen, Tuomas; Sintonen, Harri; Ranki, Annamari
Contributor: University of Helsinki, Clinicum
University of Helsinki, Department of Public Health
University of Helsinki, Clinicum
Date: 2017-06
Language: eng
Number of pages: 4
Belongs to series: Acta Dermato-Venereologica
ISSN: 0001-5555
URI: http://hdl.handle.net/10138/211840
Abstract: Cutaneous T-cell lymphomas (CTCL), especially mycosis fungoides, can be considered as a state of longstanding low-grade systemic inflammation. Many studies have focused on secondary cancers with CTCL, but information about comorbidities is limited. A total of 144 patients with CTCL at Helsinki University Central Hospital during 2005 to 2015 were studied to determine associated comorbidities and causes of death in this cohort. Compared with an age-standardized control population, the prevalence of type 2 diabetes mellitus was increased among patients with CTCL with no link to obesity. Patients with CTCL had a lower prevalence of hypertension, myocardial infarction and stroke than the control group. The 3 most common causes of death were CTCL, coronary artery disease and lung cancer. The increased risk of myocardial infarction or stroke reported previously was not detected in this patient group.
Subject: mycosis fungoides
cutaneous T-cell lymphomas
morbidity
diabetes mellitus
MYCOSIS-FUNGOIDES
CARDIOVASCULAR-DISEASE
SEZARY-SYNDROME
RISK
CLASSIFICATION
PARAPSORIASIS
CANCERS
EORTC
3142 Public health care science, environmental and occupational health
3122 Cancers
3121 General medicine, internal medicine and other clinical medicine
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