Building bridges between cellular and molecular structural biology

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http://hdl.handle.net/10138/212991

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Patwardhan , A , Brandt , R , Butcher , S J , Collinson , L , Gault , D , Grunewald , K , Hecksel , C , Huiskonen , J T , Iudin , A , Jones , M L , Korir , P K , Koster , A J , Lagerstedt , I , Lawson , C L , Mastronarde , D , McCormick , M , Parkinson , H , Rosenthal , P B , Saalfeld , S , Saibil , H R , Sarntivijai , S , Valero , I S , Subramaniam , S , Swedlow , J R , Tudose , I , Winn , M & Kleywegt , G J 2017 , ' Building bridges between cellular and molecular structural biology ' eLife , vol 6 , 25835 . DOI: 10.7554/eLife.25835

Title: Building bridges between cellular and molecular structural biology
Author: Patwardhan, Ardan; Brandt, Robert; Butcher, Sarah J.; Collinson, Lucy; Gault, David; Grunewald, Kay; Hecksel, Corey; Huiskonen, Juha T.; Iudin, Andrii; Jones, Martin L.; Korir, Paul K.; Koster, Abraham J.; Lagerstedt, Ingvar; Lawson, Catherine L.; Mastronarde, David; McCormick, Matthew; Parkinson, Helen; Rosenthal, Peter B.; Saalfeld, Stephan; Saibil, Helen R.; Sarntivijai, Sirarat; Valero, Irene Solanes; Subramaniam, Sriram; Swedlow, Jason R.; Tudose, Ilinca; Winn, Martyn; Kleywegt, Gerard J.
Contributor: University of Helsinki, Department of Biosciences
University of Helsinki, HLSC, Helsinki Life Science Center
Belongs to series: eLife
ISSN: 2050-084X
Abstract: The integration of cellular and molecular structural data is key to understanding the function of macromolecular assemblies and complexes in their in vivo context. Here we report on the outcomes of a workshop that discussed how to integrate structural data from a range of public archives. The workshop identified two main priorities: the development of tools and file formats to support segmentation (that is, the decomposition of a three-dimensional volume into regions that can be associated with defined objects), and the development of tools to support the annotation of biological structures.
Peer review status: Peer reviewed
URI: http://hdl.handle.net/10138/212991
Date: 2017-07-06
Subject: MICROSCOPY DATA
ONTOLOGY
PROTEIN
COMPLEX
VISUALIZATION
ARCHITECTURE
SYSTEM
GP120
1182 Biochemistry, cell and molecular biology
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