Impact of hypoglycaemia on patient-reported outcomes from a global, 24-country study of 27,585 people with type 1 and insulin-treated type 2 diabetes

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Khunti , K , Alsifri , S , Aronson , R , Berkovic , M C , Enters-Weijnen , C , Forsen , T , Galstyan , G , Geelhoed-Duijvestijn , P , Goldfracht , M , Gydesen , H , Kapur , R , Lalic , N , Ludvik , B , Moberg , E , Pedersen-Bjergaard , U , Ramachandran , A & HAT Investigator Grp 2017 , ' Impact of hypoglycaemia on patient-reported outcomes from a global, 24-country study of 27,585 people with type 1 and insulin-treated type 2 diabetes ' , Diabetes Research and Clinical Practice , vol. 130 , pp. 121-129 . https://doi.org/10.1016/j.diabres.2017.05.004

Title: Impact of hypoglycaemia on patient-reported outcomes from a global, 24-country study of 27,585 people with type 1 and insulin-treated type 2 diabetes
Author: Khunti, Kamlesh; Alsifri, Saud; Aronson, Ronnie; Berkovic, Maja Cigrovski; Enters-Weijnen, Catherine; Forsen, Tom; Galstyan, Gagik; Geelhoed-Duijvestijn, Petronella; Goldfracht, Margalit; Gydesen, Helge; Kapur, Rahul; Lalic, Nebojsa; Ludvik, Bernhard; Moberg, Erik; Pedersen-Bjergaard, Ulrik; Ramachandran, Ambady; HAT Investigator Grp
Contributor: University of Helsinki, Clinicum
Date: 2017-08
Language: eng
Number of pages: 9
Belongs to series: Diabetes Research and Clinical Practice
ISSN: 0168-8227
URI: http://hdl.handle.net/10138/215605
Abstract: Aims: Data on the impact of hypoglycaemia on patients' daily lives and diabetes self-management, particularly in developing countries, are lacking. The aim of this study was to assess fear of, and responses to, hypoglycaemia experienced by patients globally. Materials and methods: This non-interventional, multicentre, 4-week prospective study using self-assessment questionnaires and patient diaries consisted of 27,585 patients, >= 18 years, with type 1 diabetes (n = 8022) or type 2 diabetes (n = 19,563) treated with insulin for > 12 months, at 2004 sites in 24 countries worldwide. Results: Increased blood glucose monitoring (69.7%) and seeking medical assistance (62.0%) were the most common responses in the 4 weeks following hypoglycaemic events for patients with type 1 diabetes and type 2 diabetes, respectively. Approximately 44% of patients with type 1 diabetes or type 2 diabetes increased calorie intake in response to a hypoglycaemic episode. Following hypoglycaemia, 3.9% (type 1 diabetes) and 6.2% (type 2 diabetes) of patients took leave from work or study. Regional differences in fear of, and responses to, hypoglycaemia were evident - in particular, a lower level of hypoglycaemic fear and utilisation of healthcare resources in Northern Europe and Canada. Conclusions: Hypoglycaemia has a major impact on patients and their behaviour. These global data for the first time reveal regional variations in response to hypoglycaemia and highlight the importance of patient education and management strategies. (C) 2017 The Authors. Published by Elsevier Ireland Ltd. This is an open access article under the
Subject: HAT study
Hypoglycaemia
Observational
Insulin
Diabetes
Global
QUALITY-OF-LIFE
DOSING IRREGULARITIES
WORK PRODUCTIVITY
EVENTS
PREDICTORS
MANAGEMENT
PHYSICIANS
FREQUENCY
COHORT
CARE
3121 Internal medicine
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