Vitamin C supplementation and the common cold - Was Linus Pauling right or wrong?

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http://hdl.handle.net/10138/223748

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Hemilä , H 1997 , ' Vitamin C supplementation and the common cold - Was Linus Pauling right or wrong? ' , International Journal for Vitamin and Nutrition Research , vol. 67 , no. 5 , pp. 329-335 . < http://hdl.handle.net/10250/7980 >

Title: Vitamin C supplementation and the common cold - Was Linus Pauling right or wrong?
Author: Hemilä, Harri
Contributor: University of Helsinki, Department of Public Health
Date: 1997
Language: eng
Number of pages: 7
Belongs to series: International Journal for Vitamin and Nutrition Research
ISSN: 0300-9831
URI: http://hdl.handle.net/10138/223748
Abstract: In 1970 Linus Pauling claimed that vitamin C prevents and alleviates the episodes of the common cold. Pauling was correct in concluding from trials published up till then, that in general vitamin C does have biological effects on the common cold, but he was rather over-optimistic as regards the size of benefit. His quantitative conclusions were based on a single placebo-controlled trial on schoolchildren in a skiing camp in the Swiss Alps, in which a significant decrease in common cold incidence and duration in the group administered 1 g/day of vitamin C was found. As children in a skiing camp are not a representative sample of the general population, Pauling's extrapolation to the population at large was too bold, erring as to the magnitude of the effect. Nevertheless, Pauling's general conclusion that vitamin C has physiological effects on the common cold is of major importance as it conflicts with the prevailing consensus that the only physiological effect of vitamin C on human beings is to prevent scurvy.
Subject: ascorbic acid
upper respiratory infections
controlled trials
children
ASCORBIC-ACID
RE-EVALUATION
CANCER
SCHOOLCHILDREN
CHOLESTEROL
ILLNESS
HEALTH
TRIAL
314 Health sciences
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