Differences and similarities of risk factors for suicidal ideation and attempts among patients with depressive or bipolar disorders

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Aaltonen , K , Naatanen , P , Heikkinen , M , Koivisto , M , Baryshnikoy , I , Karpov , B , Oksanen , J , Melartin , T , Suominen , K , Joffe , G , Paunio , T & Isometsa , E 2016 , ' Differences and similarities of risk factors for suicidal ideation and attempts among patients with depressive or bipolar disorders ' Journal of Affective Disorders , vol. 193 , pp. 318-330 . DOI: 10.1016/j.jad.2015.12.033

Title: Differences and similarities of risk factors for suicidal ideation and attempts among patients with depressive or bipolar disorders
Author: Aaltonen, Kari; Naatanen, Petri; Heikkinen, Martti; Koivisto, Maaria; Baryshnikoy, Ilya; Karpov, Boris; Oksanen, Jorma; Melartin, Tarja; Suominen, Kirsi; Joffe, Grigori; Paunio, Tiina; Isometsa, Erkki
Contributor: University of Helsinki, Department of Psychiatry
University of Helsinki, Department of Psychology (-2009)
University of Helsinki, Department of Psychiatry
University of Helsinki, Department of Psychiatry
University of Helsinki, Department of Psychiatry
University of Helsinki, Department of Psychiatry
University of Helsinki, Clinicum
University of Helsinki, Clinicum
University of Helsinki, Department of Psychiatry
University of Helsinki, Department of Psychiatry
University of Helsinki, Department of Psychiatry
Date: 2016-03-15
Language: eng
Number of pages: 13
Belongs to series: Journal of Affective Disorders
ISSN: 0165-0327
URI: http://hdl.handle.net/10138/223877
Abstract: Background: Substantial literature exists on risk factors for suicidal behaviour. However, their comparative strength, independence and specificity for either suicidal ideation or suicide attempt(s) remain unclear. Methods: The Helsinki University Psychiatric Consortium (HUPC) Study surveyed 287 psychiatric care patients with ICD-10-DCR depressive or bipolar disorders about lifetime suicidal behaviour, developmental history and attachment style, personality and psychological traits, current and lifetime symptom profiles, and life events. Psychiatric records were used to confirm diagnosis and complement information on suicide attempts. Multinomial regression models predicting lifetime suicidal ideation and single or repeated suicide attempts were generated. Results: Overall, 21.6% patients had no lifetime suicidal behaviour, 33.8% had lifetime suicide ideation without attempts, and 17.1% had a single and 27.5% repeated suicide attempts. In univariate analyses, lifetime suicidal behaviour was associated with numerous factors. In multivariate models, suicidal ideation was independently predicted by younger age, severe depressive disorder, bipolar disorder type II/nos, hopelessness, and childhood physical abuse. Repeated suicide attempts were independently predicted by younger age, female sex, severe depressive disorder with or without psychotic symptoms, bipolar disorder type II/nos, alcohol use disorder, borderline personality disorder traits, and childhood physical abuse. Limitations: Cross-sectional and retrospective study design, utilization of clinical diagnoses, and relatively low response rate. Conclusions: Risk factors for suicidal ideation and attempts may diverge both qualitatively and in terms of dose response. When effects of risk factors from multiple domains are concurrently examined, proximal clinical characteristics remain the most robust. All risk factors cluster into the group of repeated attempters. (C) 2015 Elsevier B.V. All rights reserved.
Subject: Suicidal behaviour
Suicide attempt
Depressive disorder
Bipolar disorder
Risk factor
BORDERLINE-PERSONALITY-DISORDER
POSTTRAUMATIC-STRESS-DISORDER
MCLEAN SCREENING INSTRUMENT
NATIONAL COMORBIDITY SURVEY
ADULT MENTAL-DISORDERS
IMPAIRMENT SCALE OASIS
CHILDHOOD MALTREATMENT
II DISORDERS
PSYCHIATRIC-DISORDERS
MAJOR DEPRESSION
3124 Neurology and psychiatry
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