Current concepts in chronic inflammatory diseases : Interactions between microbes, cellular metabolism, and inflammation

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dc.contributor.author Garn, Holger
dc.contributor.author Bahn, Sabine
dc.contributor.author Baune, Bernhard T.
dc.contributor.author Binder, Elisabeth B.
dc.contributor.author Bisgaard, Hans
dc.contributor.author Chatila, Talal A.
dc.contributor.author Chavakis, Triantafyllos
dc.contributor.author Culmsee, Carsten
dc.contributor.author Dannlowski, Udo
dc.contributor.author Gay, Steffen
dc.contributor.author Gern, James
dc.contributor.author Haahtela, Tari
dc.contributor.author Kircher, Tilo
dc.contributor.author Mueller-Ladner, Ulf
dc.contributor.author Neurath, Markus F.
dc.contributor.author Preissner, Klaus T.
dc.contributor.author Reinhardt, Christoph
dc.contributor.author Rook, Graham
dc.contributor.author Russell, Shannon
dc.contributor.author Schmeck, Bernd
dc.contributor.author Stappenbeck, Thaddeus
dc.contributor.author Steinhoff, Ulrich
dc.contributor.author van Os, Jim
dc.contributor.author Weiss, Scott
dc.contributor.author Zemlin, Michael
dc.contributor.author Renz, Harald
dc.date.accessioned 2017-09-14T09:56:35Z
dc.date.available 2021-12-17T18:48:35Z
dc.date.issued 2016-07
dc.identifier.citation Garn , H , Bahn , S , Baune , B T , Binder , E B , Bisgaard , H , Chatila , T A , Chavakis , T , Culmsee , C , Dannlowski , U , Gay , S , Gern , J , Haahtela , T , Kircher , T , Mueller-Ladner , U , Neurath , M F , Preissner , K T , Reinhardt , C , Rook , G , Russell , S , Schmeck , B , Stappenbeck , T , Steinhoff , U , van Os , J , Weiss , S , Zemlin , M & Renz , H 2016 , ' Current concepts in chronic inflammatory diseases : Interactions between microbes, cellular metabolism, and inflammation ' , Journal of Allergy and Clinical Immunology , vol. 138 , no. 1 , pp. 47-56 . https://doi.org/10.1016/j.jaci.2016.02.046
dc.identifier.other PURE: 67014076
dc.identifier.other PURE UUID: 828c7206-944c-422a-8fa5-d0659a43d649
dc.identifier.other WOS: 000379659100005
dc.identifier.other Scopus: 84990878443
dc.identifier.uri http://hdl.handle.net/10138/224107
dc.description.abstract Recent research indicates that chronic inflammatory diseases, including allergies and autoimmune and neuropsychiatric diseases, share common pathways of cellular and molecular dysregulation. It was the aim of the International von-Behring-Rontgen Symposium (October 16-18, 2014, in Marburg, Germany) to discuss recent developments in this field. These include a concept of biodiversity; the contribution of urbanization, lifestyle factors, and nutrition (eg, vitamin D); and new mechanisms of metabolic and immune dysregulation, such as extracellular and intracellular RNAs and cellular and mitochondrial stress. Epigenetic mechanisms contribute further to altered gene expression and therefore to the development of chronic inflammation. These novel findings provide the foundation for further development of preventive and therapeutic strategies. en
dc.format.extent 10
dc.language.iso eng
dc.relation.ispartof Journal of Allergy and Clinical Immunology
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Chronic inflammation
dc.subject immune dysregulation
dc.subject metabolism
dc.subject environment
dc.subject epigenetics
dc.subject stress
dc.subject biodiversity
dc.subject EARLY-LIFE
dc.subject VITAMIN-D
dc.subject RHEUMATOID-ARTHRITIS
dc.subject EXTRACELLULAR RNA
dc.subject SCHIZOPHRENIA-PATIENTS
dc.subject INTESTINAL MICROBIOTA
dc.subject IMMUNE-RESPONSES
dc.subject CHILDHOOD ASTHMA
dc.subject GUT MICROBIOTA
dc.subject ANTIBIOTIC USE
dc.subject 3121 General medicine, internal medicine and other clinical medicine
dc.title Current concepts in chronic inflammatory diseases : Interactions between microbes, cellular metabolism, and inflammation en
dc.type Article
dc.contributor.organization Clinicum
dc.contributor.organization Department of Dermatology, Allergology and Venereology
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.jaci.2016.02.046
dc.relation.issn 0091-6749
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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