Trends in the 15D health-related quality of life over the first year following diagnosis of head and neck cancer

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Aro , K , Back , L , Loimu , V , Saarilahti , K , Rogers , S , Sintonen , H , Roine , R P A & Makitie , A 2016 , ' Trends in the 15D health-related quality of life over the first year following diagnosis of head and neck cancer ' , European Archives of Oto-Rhino-Laryngology , vol. 273 , no. 8 , pp. 2141-2150 . https://doi.org/10.1007/s00405-015-3732-4

Title: Trends in the 15D health-related quality of life over the first year following diagnosis of head and neck cancer
Author: Aro, Katri; Back, L.; Loimu, V.; Saarilahti, K.; Rogers, S.; Sintonen, H.; Roine, Risto Paavo Antero; Makitie, Antti
Contributor organization: Korva-, nenä- ja kurkkutautien klinikka
Department of Ophthalmology and Otorhinolaryngology
Clinicum
Department of Oncology
Harri Sintonen Research Group
Department of Public Health
Date: 2016-08
Language: eng
Number of pages: 10
Belongs to series: European Archives of Oto-Rhino-Laryngology
ISSN: 0937-4477
DOI: https://doi.org/10.1007/s00405-015-3732-4
URI: http://hdl.handle.net/10138/224113
Abstract: Management of head and neck cancer influences both physical and mental wellbeing. Measuring the health-related quality of life (HRQoL) is important, as various treatment modalities are associated with significant morbidity and mortality. In this prospective cohort study, we tested the feasibility of the generic 15D HRQoL instrument in 214 head and neck cancer patients managed with surgery, definitive (chemo)radiotherapy, or with combined modality treatment. HRQoL was assessed at baseline and three times after treatment onset during 1 year, and compared with that of general population standardized for age and sex. At baseline, the patients' mean 15D score was significantly worse compared with general population. Overall HRQoL was at lowest at 3 months after treatment onset, it gradually improved towards 12 months but never reached baseline levels. The dimensions "vitality", "distress", "depression" and "sexual activity" showed marked deterioration at 3 months after the treatment onset, but improved gradually during 12 months. The 15D instrument seems useful for evaluation of HRQoL of head and neck cancer patients. Dimensions reflecting mental wellbeing improved gradually after 3 months, but they seldom reached baseline levels. The support for patients at the time of diagnosis, during treatment, and recovery is emphasized.
Subject: Head and neck cancer
Health-related quality of life
Surgery
Radiotherapy
Chemoradiotherapy
FACTORS AFFECTING PLACEMENT
GASTROSTOMY TUBE PLACEMENT
IMPACT
RADIOTHERAPY
DISSECTION
OUTCOMES
CHEMORADIATION
DEPENDENCE
CARCINOMA
3125 Otorhinolaryngology, ophthalmology
Peer reviewed: Yes
Usage restriction: openAccess
Self-archived version: publishedVersion


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