Novel Detector Technologies for Medical Applications at the Example of Tumor Detection in BNCT

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http://urn.fi/URN:ISBN:978-951-51-3692-3
Julkaisun nimi: Novel Detector Technologies for Medical Applications at the Example of Tumor Detection in BNCT
Tekijä: Winkler, Alexander
Muu tekijä: Helsingin yliopisto, matemaattis-luonnontieteellinen tiedekunta, fysiikan laitos
Opinnäytteen taso: Väitöskirja (artikkeli)
Tiivistelmä: The next evolutionary step in medical imaging and radiation therapy is to employ novel detector technologies capable of photon counting operations. These detectors allow to acquire the spectrum of the radiation for each pixel. Currently used energy integrating detectors do not allow this. Two types of detector materials capable of photon counting operation are discussed in this work. With the result that the detector technology based on CdTe and CdZnTe is more matured than GaAs. The spectral information of photon counting detectors can be used for numerous applications and diagnostic improvements. A distinct example is presented for boron neutron capture therapy (BNCT). This therapy lacks an accurate real time method to determine the 10B concentration within the patient. Previous approaches failed because of the low signal to noise ratio of the used signal. A method has been proposed to improve this therapy by employing CdTe based photon counting detectors. These detectors allow detection of a secondary signal with a higher signal to noise ratio. Additionally, efforts to produce CdTe based photon counting detector arrays, for medical applications, are described.The next evolutionary step in medical imaging and radiation therapy is to use novel detector technologies capable of detecting the "colour" of X-rays. These devices are called photon counting detectors. Currently used energy integrating detectors do not allow this. Two types of detector materials capable of photon counting operation are discussed in this work. With the result that the detector technology based on CdTe and CdZnTe is more matured than GaAs. These photon counting detectors can be used for numerous applications and diagnostic improvements. A distinct example is presented for boron neutron capture therapy (BNCT). This therapy lacks an accurate method to determine the 10B concentration within the patient and during the treatment. Previous approaches failed because on the low signal strength (signal to noise ratio). In this work a method has been proposed to improve the therapy by employing CdTe based photon counting detectors. These detectors allow detection of another signal that is stronger (higher signal to noise ratio). Additionally, efforts to produce CdTe based photon counting detector arrays, for medical applications, are described.
URI: URN:ISBN:978-951-51-3692-3
http://hdl.handle.net/10138/224382
Päiväys: 2017-10-20
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