Gestational hypertension and chronic hypertension on the risk of diabetes among gestational diabetes women

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Yuan , X , Liu , H , Wang , L , Zhang , S , Zhang , C , Leng , J , Dong , L , Lv , L , Lv , F , Tian , H , Qi , L , Tuomilehto , J & Hu , G 2016 , ' Gestational hypertension and chronic hypertension on the risk of diabetes among gestational diabetes women ' , Journal of Diabetes and its Complications , vol. 30 , no. 7 , pp. 1269-1274 . https://doi.org/10.1016/j.jdiacomp.2016.04.025

Title: Gestational hypertension and chronic hypertension on the risk of diabetes among gestational diabetes women
Author: Yuan, Xiaojing; Liu, Huikun; Wang, Leishen; Zhang, Shuang; Zhang, Cuiping; Leng, Junhong; Dong, Ling; Lv, Li; Lv, Fengjun; Tian, Huiguang; Qi, Lu; Tuomilehto, Jaakko; Hu, Gang
Contributor organization: Jaakko Tuomilehto Research Group
Department of Public Health
Clinicum
Date: 2016
Language: eng
Number of pages: 6
Belongs to series: Journal of Diabetes and its Complications
ISSN: 1056-8727
DOI: https://doi.org/10.1016/j.jdiacomp.2016.04.025
URI: http://hdl.handle.net/10138/224406
Abstract: Aims: We aimed to examine the association of gestational hypertension and chronic hypertension at the inter-conception examination with type 2 diabetes risk among women with a history of gestational diabetes. Methods: We conducted a population-based study among 1261 women who had a history of gestational diabetes at 1-5 years after delivery in Tianjin, China. Logistic regression or Cox regression was used to assess the associations of gestational hypertension and chronic hypertension at the inter-conception examination with pre-diabetes and type 2 diabetes risks. Results: Gestational diabetic women who had a history of gestational hypertension but did not use antihypertensive drugs during pregnancy had a 3.94-fold higher risk (95% CI: 1.94-8.02) of developing type 2 diabetes compared with those who were normotensive in index pregnancy. Compared with gestational diabetic women who had normal blood pressure at the inter-conception examination, hypertensive women at the inter-conception examination were 3.38 times (95% CI: 1.66-6.87) and 2.97 times (95% CI: 1.75-5.05) more likely to develop diabetes and prediabetes, respectively. The odds ratios of type 2 diabetes and prediabetes associated with each 5 mmHg increase in systolic blood pressure were 125 (95% CI: 1.03-1.51) and 120 (95% CI: 1.06-135). Each 5 mmHg increase in diastolic blood pressure contributed to a 1.49-fold higher risk (95% CI: 1.18-1.88) for type 2 diabetes and a 1.42-fold higher risk (95% CI: 1.22-1.65) for prediabetes. Conclusions: For women with prior gestational diabetes, gestational hypertension and chronic hypertension at the inter-conception examination were risk factors for type 2 diabetes. (C) 2016 Elsevier Inc. All rights reserved.
Subject: Hypertension
Gestational hypertension
Diabetes
Gestational diabetes
Incidence
PREGNANCY-INDUCED HYPERTENSION
INSULIN-RESISTANCE
CHINESE WOMEN
MICROVASCULAR DYSFUNCTION
CARDIOVASCULAR-DISEASE
BLOOD-PRESSURE
FOLLOW-UP
MELLITUS
OBESITY
ASSOCIATION
3121 General medicine, internal medicine and other clinical medicine
3142 Public health care science, environmental and occupational health
Peer reviewed: Yes
Usage restriction: openAccess
Self-archived version: publishedVersion


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