Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8(+) T-cell response, prominent infiltration of CD8(+) lymphocytes and Th1 type polarization

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Ranki , T , Joensuu , T , Jaeger , E , Karbach , J , Wahle , C , Kairemo , K , Alanko , T , Partanen , K , Turkki , R , Linder , N , Lundin , J , Ristimaki , A , Kankainen , M , Hemminki , A , Backman , C , Dienel , K , von Euler , M , Haavisto , E , Hakonen , T , Juhila , J , Jaderberg , M , Priha , P , Vassilev , L , Vuolanto , A & Pesonen , S 2014 , ' Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8(+) T-cell response, prominent infiltration of CD8(+) lymphocytes and Th1 type polarization ' , OncoImmunology , vol. 3 , no. 10 , 958937 . https://doi.org/10.4161/21624011.2014.958937

Title: Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8(+) T-cell response, prominent infiltration of CD8(+) lymphocytes and Th1 type polarization
Author: Ranki, Tuuli; Joensuu, Timo; Jaeger, Elke; Karbach, Julia; Wahle, Claudia; Kairemo, Kalevi; Alanko, Tuomo; Partanen, Kaarina; Turkki, Riku; Linder, Nina; Lundin, Johan; Ristimaki, Ari; Kankainen, Matti; Hemminki, Akseli; Backman, Charlotta; Dienel, Kasper; von Euler, Mikael; Haavisto, Elina; Hakonen, Tiina; Juhila, Juuso; Jaderberg, Magnus; Priha, Petri; Vassilev, Lotta; Vuolanto, Antti; Pesonen, Sari
Contributor organization: Institute for Molecular Medicine Finland
Haartman Institute (-2014)
Department of Pathology
Research Programs Unit
Genome-Scale Biology (GSB) Research Program
Clinicum
Gastrointestinal tumorigenesis
Date: 2014
Language: eng
Number of pages: 4
Belongs to series: OncoImmunology
ISSN: 2162-4011
DOI: https://doi.org/10.4161/21624011.2014.958937
URI: http://hdl.handle.net/10138/225325
Subject: Adenovirus
antitumor immunity
cytotoxic immunotherapy
GM-CSF
Th1 polarization
tumor infiltrating lymphocytes
CANCER
TOLERANCE
THERAPY
3122 Cancers
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


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