Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8(+) T-cell response, prominent infiltration of CD8(+) lymphocytes and Th1 type polarization

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Ranki , T , Joensuu , T , Jaeger , E , Karbach , J , Wahle , C , Kairemo , K , Alanko , T , Partanen , K , Turkki , R , Linder , N , Lundin , J , Ristimaki , A , Kankainen , M , Hemminki , A , Backman , C , Dienel , K , von Euler , M , Haavisto , E , Hakonen , T , Juhila , J , Jaderberg , M , Priha , P , Vassilev , L , Vuolanto , A & Pesonen , S 2014 , ' Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8(+) T-cell response, prominent infiltration of CD8(+) lymphocytes and Th1 type polarization ' , OncoImmunology , vol. 3 , no. 10 , 958937 . https://doi.org/10.4161/21624011.2014.958937

Title: Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8(+) T-cell response, prominent infiltration of CD8(+) lymphocytes and Th1 type polarization
Author: Ranki, Tuuli; Joensuu, Timo; Jaeger, Elke; Karbach, Julia; Wahle, Claudia; Kairemo, Kalevi; Alanko, Tuomo; Partanen, Kaarina; Turkki, Riku; Linder, Nina; Lundin, Johan; Ristimaki, Ari; Kankainen, Matti; Hemminki, Akseli; Backman, Charlotta; Dienel, Kasper; von Euler, Mikael; Haavisto, Elina; Hakonen, Tiina; Juhila, Juuso; Jaderberg, Magnus; Priha, Petri; Vassilev, Lotta; Vuolanto, Antti; Pesonen, Sari
Contributor: University of Helsinki, Oncos Therapeut
University of Helsinki, Docrates Canc Ctr
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Haartman Institute (-2014)
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Oncos Therapeutics Oy
Date: 2014
Language: eng
Number of pages: 4
Belongs to series: OncoImmunology
ISSN: 2162-4011
URI: http://hdl.handle.net/10138/225325
Subject: Adenovirus
antitumor immunity
cytotoxic immunotherapy
GM-CSF
Th1 polarization
tumor infiltrating lymphocytes
CANCER
TOLERANCE
THERAPY
3122 Cancers
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