Efficacy of progressive aquatic resistance training for tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis : a randomised controlled trial

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dc.contributor.author Munukka, M.
dc.contributor.author Waller, B.
dc.contributor.author Rantalainen, T.
dc.contributor.author Hakkinen, A.
dc.contributor.author Nieminen, M. T.
dc.contributor.author Lammentausta, E.
dc.contributor.author Kujala, U. M.
dc.contributor.author Paloneva, J.
dc.contributor.author Sipila, S.
dc.contributor.author Peuna, A.
dc.contributor.author Kautiainen, H.
dc.contributor.author Selanne, H.
dc.contributor.author Kiviranta, I.
dc.contributor.author Heinonen, A.
dc.date.accessioned 2017-10-21T21:07:11Z
dc.date.available 2021-12-17T18:48:53Z
dc.date.issued 2016-10
dc.identifier.citation Munukka , M , Waller , B , Rantalainen , T , Hakkinen , A , Nieminen , M T , Lammentausta , E , Kujala , U M , Paloneva , J , Sipila , S , Peuna , A , Kautiainen , H , Selanne , H , Kiviranta , I & Heinonen , A 2016 , ' Efficacy of progressive aquatic resistance training for tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis : a randomised controlled trial ' , Osteoarthritis and Cartilage , vol. 24 , no. 10 , pp. 1708-1717 . https://doi.org/10.1016/j.joca.2016.05.007
dc.identifier.other PURE: 70157401
dc.identifier.other PURE UUID: 9bd85215-65e7-47ba-8ccf-371583389a4f
dc.identifier.other WOS: 000384130400004
dc.identifier.other Scopus: 84976490747
dc.identifier.uri http://hdl.handle.net/10138/225972
dc.description.abstract Objective: To study the efficacy of aquatic resistance training on biochemical composition of tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis (OA). Design: Eighty seven volunteer postmenopausal women, aged 60-68 years, with mild knee OA (Kellgren-Lawrence grades I/II and knee pain) were recruited and randomly assigned to an intervention (n = 43) and control (n = 44) group. The intervention group participated in 48 supervised aquatic resistance training sessions over 16 weeks while the control group maintained usual level of physical activity. The biochemical composition of the medial and lateral tibiofemoral cartilage was estimated using single-slice transverse relaxation time (T2) mapping and delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC index). Secondary outcomes were cardiorespiratory fitness, isometric knee extension and flexion force and knee injury and OA outcome (KOOS) questionnaire. Results: After 4-months aquatic training, there was a significant decrease in both T2 -1.2 ms (95% confidence interval (CI): -2.3 to -0.1, P = 0.021) and dGEMRIC index -23 ms (-43 to -3, P = 0.016) in the training group compared to controls in the full thickness posterior region of interest (ROI) of the medial femoral cartilage. Cardiorespiratory fitness significantly improved in the intervention group by 9.8% (P = 0.010). Conclusions: Our results suggest that, in postmenopausal women with mild knee OA, the integrity of the collagen-interstitial water environment (T2) of the tibiofemoral cartilage may be responsive to low shear and compressive forces during aquatic resistance training. More research is required to understand the exact nature of acute responses in dGEMRIC index to this type of loading. Further, aquatic resistance training improves cardiorespiratory fitness. (C) 2016 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved. en
dc.format.extent 10
dc.language.iso eng
dc.relation.ispartof Osteoarthritis and Cartilage
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Osteoarthritis
dc.subject Aquatic exercise
dc.subject Magnetic resonance imaging (MRI)
dc.subject Cartilage
dc.subject Randomised controlled trial
dc.subject GADOLINIUM-ENHANCED MRI
dc.subject ARTICULAR-CARTILAGE
dc.subject GLYCOSAMINOGLYCAN DISTRIBUTION
dc.subject PATELLAR CARTILAGE
dc.subject PHYSICAL-ACTIVITY
dc.subject QUANTITATIVE MRI
dc.subject RUNNING EXERCISE
dc.subject JOINT
dc.subject THICKNESS
dc.subject BONE
dc.subject 3126 Surgery, anesthesiology, intensive care, radiology
dc.title Efficacy of progressive aquatic resistance training for tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis : a randomised controlled trial en
dc.type Article
dc.contributor.organization Department of General Practice and Primary Health Care
dc.contributor.organization Clinicum
dc.contributor.organization Department of Surgery
dc.contributor.organization I kirurgian klinikka (Töölö)
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.joca.2016.05.007
dc.relation.issn 1063-4584
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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