Letter to the Editor : [Letter]

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Hemilä , H 2006 , ' Letter to the Editor : [Letter] ' , Nutrition Reviews , vol. 64 , no. 10 , pp. 476-477 . https://doi.org/10.1111/j.1753-4887.2006.tb00179.x

Title: Letter to the Editor : [Letter]
Author: Hemilä, Harri
Contributor: University of Helsinki, Department of Public Health
Date: 2006
Language: eng
Number of pages: 2
Belongs to series: Nutrition Reviews
ISSN: 0029-6643
URI: http://hdl.handle.net/10138/228097
Abstract: The effect of nutrition on exercise-induced immunodepression was reviewed by Gleeson. In the vitamin E section of the review, he discussed the findings of Graat et al.’s trial (N = 652) with 60 year-old noninstitutionalized participants and Meydani et al.’s trial (N = 617) with 65 year-old nursing home residents. Gleeson commented that self-evaluation of the common cold might have been unreliable in Graat’s trial; however, Gwaltney states in a major textbook of infectious diseases that “the manifestations of the common cold are so typical and familiar that self-diagnosis by the patient is usually correct”. Furthermore, even if the outcome may be inaccurate, such inaccuracy cannot explain the increase in the number of participants with fever (P = 0.009) by vitamin E supplementation in a trial that is double-blind. Irrespective of etiology, the net increase in fever indicates unquestionable harm in those participants. There is evidence that vitamins C and E may affect, under some conditions, the risk of respiratory infections in people who are under physical stress, but assessment of the practical significance of these findings needs further work.
Subject: 314 Health sciences
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