Vitamin C in Clinical Therapeutics

Show full item record



Hemilä , H 2017 , ' Vitamin C in Clinical Therapeutics ' , Clinical Therapeutics , vol. 39 , no. 10 , pp. 2110-2112 .

Title: Vitamin C in Clinical Therapeutics
Author: Hemilä, Harri
Contributor organization: Harri Hemilä / Principal Investigator
Department of Public Health
University of Helsinki
Date: 2017-10
Language: eng
Number of pages: 3
Belongs to series: Clinical Therapeutics
ISSN: 0149-2918
Abstract: I read with great interest Dr Shader’s editorial that discussed vitamin C. I share many of his concerns about methodologic and statistical problems in the vitamin C trials. Nevertheless, some of my conclusions of the field are more positive. On the basis of the currently published findings of randomized controlled trials (RCTs), there is no justification to encourage general populations of Western countries to take vitamin C regularly to prevent colds, cancers, or cardiovascular diseases. Vitamin C, however, is a water-soluble antioxidant, and it is possible that its administration may have effects on people who have elevated levels of oxidative stress in their body. Oxidative stress is increased, for example, by heavy exertion, infections, and cardiac operations. Furthermore, the level of vitamin C synthesis is increased by various forms of stress in those animals that synthesize their own vitamin C. By analogy, larger vitamin C intakes might be beneficial for humans when they are under some forms of stress because humans are unable to synthesize their own vitamin C.
Subject: 3121 General medicine, internal medicine and other clinical medicine
317 Pharmacy
Ascorbic Acid
Common Cold
Atrial Fibrillation
Peer reviewed: No
Usage restriction: openAccess
Self-archived version: acceptedVersion

Files in this item

Total number of downloads: Loading...

Files Size Format View
2017_ClinicalTherapeutics.pdf 72.32Kb PDF View/Open
1_s2.0_S0149291817308949_main.pdf 322.4Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record