Integrated Cardio-Respiratory Control : Insight in Diabetes

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http://hdl.handle.net/10138/229903

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Bernardi , L & Bianchi , L 2016 , ' Integrated Cardio-Respiratory Control : Insight in Diabetes ' , Current diabetes reports. , vol. 16 , no. 11 , 107 . https://doi.org/10.1007/s11892-016-0804-9

Title: Integrated Cardio-Respiratory Control : Insight in Diabetes
Author: Bernardi, Luciano; Bianchi, Lucio
Contributor: University of Helsinki, Research Programs Unit
Date: 2016-11
Language: eng
Number of pages: 9
Belongs to series: Current diabetes reports.
ISSN: 1534-4827
URI: http://hdl.handle.net/10138/229903
Abstract: Autonomic dysfunction is a frequent and relevant complication of diabetes mellitus, as it is associated with increased morbidity and mortality. In addition, it is today considered as predictive of the most severe diabetic complications, like nephropathy and retinopathy. The classical methods of screening are the cardiovascular reflex tests and were originally interpreted as evidence of nerve damage. A more modern approach, based on the integrated control of cardiovascular and respiratory function, reveals that these abnormalities are to a great extent functional, at least in the early stage of the disease, thus suggesting new potential interventions. Therefore, this review aims to go further investigating how the imbalance of the autonomic nervous system is altered and can be influenced in many chronic pathologies through a global view of cardio-respiratory and metabolic interactions and how the same mechanisms are applicable to diabetes.
Subject: Chemoreflex
Baroreflex
Heart rate variability
Diabetic neuropathy
Hypoxia
Autonomic nervous system
Cardio-respiratory interactions
CHRONIC HEART-FAILURE
OBSTRUCTIVE SLEEP-APNEA
CARDIOVASCULAR AUTONOMIC NEUROPATHY
SYMPATHETIC-NERVE ACTIVITY
SPONTANEOUS BAROREFLEX SENSITIVITY
POSITIVE AIRWAY PRESSURE
CHRONIC-RENAL-FAILURE
VENTILATORY RESPONSE
BLOOD-PRESSURE
PERIPHERAL CHEMOREFLEX
3121 General medicine, internal medicine and other clinical medicine
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