Associations of night-time road traffic noise with carotid intima-media thickness and blood pressure : The Whitehall II and SABRE study cohorts

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Halonen , J I , Dehbi , H-M , Hansell , A L , Gulliver , J , Fecht , D , Blangiardo , M , Kelly , F J , Chaturvedi , N , Kivimaki , M & Tonne , C 2017 , ' Associations of night-time road traffic noise with carotid intima-media thickness and blood pressure : The Whitehall II and SABRE study cohorts ' , Environment International , vol. 98 , pp. 54-61 . https://doi.org/10.1016/j.envint.2016.09.023

Title: Associations of night-time road traffic noise with carotid intima-media thickness and blood pressure : The Whitehall II and SABRE study cohorts
Author: Halonen, Jaana I.; Dehbi, Hakim-Moulay; Hansell, Anna L.; Gulliver, John; Fecht, Daniela; Blangiardo, Marta; Kelly, Frank J.; Chaturvedi, Nish; Kivimaki, Mika; Tonne, Cathryn
Contributor: University of Helsinki, Clinicum
Date: 2017-01
Language: eng
Number of pages: 8
Belongs to series: Environment International
ISSN: 0160-4120
URI: http://hdl.handle.net/10138/230301
Abstract: Background: Road traffic noise has been linked to increased risk of stroke, for which hypertension and carotid intima-media thickness (cIMT) are risk factors. A link between traffic noise and hypertension has been established, but there are few studies on blood pressure and no studies on cIMT. Objectives: To examine cross-sectional associations for long-term exposure to night-time noise with cIMT, systolic blood pressure (SBP), diastolic blood pressure (DBP) and hypertension. Methods: The study population consisted of 2592 adults from the Whitehall II and SABRE cohort studies living within Greater London who had cIMT, SBP and DBP measured. Exposure to night-time road traffic noise (A-weighted dB, referred to as dBA) was estimated at each participant's residential postcode centroid. Results: Mean night-time road noise levels were 52 dBA (SD=4). In the pooled analysis adjusted for cohort, sex, age, ethnicity, marital status, smoking, area-level deprivation and NOx there was a 9.1 mu m (95% CI: -7.1, 25.2) increase in cIMT in association with 10 dBA increase in night-time noise. Analyses by noise categories of 5560 dBA (16.2 mu m, 95% CI:-8.7, 41.2), and N60 dBA (21.2 mu m, 95% CI:-2.5, 44.9) vs. 60 dBA vs. Conclusions: After adjustments, including for air pollution, the association between night-time road traffic noise and cIMT was only observed among non-medication users but associations with blood pressure and hypertension were largely null. (C) 2016 Elsevier Ltd. All rights reserved.
Subject: Cardiovascular
Cohort study
Epidemiology
Hypertension
Traffic noise
PARTICULATE AIR-POLLUTION
LONG-TERM EXPOSURE
CARDIOVASCULAR-DISEASE
HYPERTENSION
ADULTS
ATHEROSCLEROSIS
RISK
METAANALYSIS
MORTALITY
PROFILE
3142 Public health care science, environmental and occupational health
3121 General medicine, internal medicine and other clinical medicine
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