Cystic echinococcosis : Future perspectives of molecular epidemiology

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Ito , A , Nakao , M , Lavikainen , A & Hoberg , E 2017 , ' Cystic echinococcosis : Future perspectives of molecular epidemiology ' , Acta Tropica , vol. 165 , pp. 3-9 . https://doi.org/10.1016/j.actatropica.2016.05.013

Title: Cystic echinococcosis : Future perspectives of molecular epidemiology
Author: Ito, Akira; Nakao, Minoru; Lavikainen, Antti; Hoberg, Eric
Contributor: University of Helsinki, Medicum
Date: 2017-01
Language: eng
Number of pages: 7
Belongs to series: Acta Tropica
ISSN: 0001-706X
URI: http://hdl.handle.net/10138/231665
Abstract: Human cystic echinococcosis (CE) has been considered to be caused predominantly by Echinococcus granulosus sensu stricto (the dog-sheep strain). Molecular approaches' on CE, however, have revealed that human cases are also commonly caused by another species, Echinococcus canadensis. All indices for classification and standardization of CE pathology including available images, epidemiology, diagnostics and treatment are currently based largely on a mixture of infections which include at least E. granulosus s.s. and E. canadensis. Involvement of other species of Echinococcus in CE including E. ortleppi or otherwise cryptic diversity demonstrated recently in Africa requires further elucidation. Molecular identification of the causative species in CE cases is essential for better understanding of pathogenesis and disease. This article stresses the importance of molecular species identification of human CE as a foundation for re-evaluation of evidence-based epidemiology. (C) 2016 Elsevier B.V. All rights reserved.
Subject: Cystic echinococcosis
Echinococcus granulosus sensu stricto
Echinococcus canadensis
Echinococcus ortleppi
Echinococcus felidis
Molecular identification
GRANULOSUS-SENSU-STRICTO
POLYMERASE-CHAIN-REACTION
FINE-NEEDLE-ASPIRATION
GENUS ECHINOCOCCUS
HYDATID-DISEASE
GENETIC-CHARACTERIZATION
CANADENSIS G7
PARASITIC ZOONOSES
CESTODA TAENIIDAE
HUMAN INFECTION
3142 Public health care science, environmental and occupational health
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