MAGIC polymer gel for dosimetric verification in boron neutron capture therapy

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http://hdl.handle.net/10138/232654

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Uusi-Simola , J , Heikkinen , S , Kotiluoto , P , Seren , T , Seppälä , T , Auterinen , I & Savolainen , S 2007 , ' MAGIC polymer gel for dosimetric verification in boron neutron capture therapy ' Journal of applied clinical medical physics , vol. 8 , no. 2 , pp. 114-123 . DOI: 10.1120/jacmp.v8i2.2409

Titel: MAGIC polymer gel for dosimetric verification in boron neutron capture therapy
Författare: Uusi-Simola, Jouni; Heikkinen, Sami; Kotiluoto, Petri; Seren, Tom; Seppälä, Tiina; Auterinen, Iiro; Savolainen, Sauli
Medarbetare: University of Helsinki, Sauli Savolainen / Principal Investigator
University of Helsinki, Department of Chemistry
University of Helsinki, Sauli Savolainen / Principal Investigator
University of Helsinki, Accelerator Laboratory (Department of Physics) (-2009)
Datum: 2007
Språk: eng
Sidantal: 10
Tillhör serie: Journal of applied clinical medical physics
ISSN: 1526-9914
Permanenta länken (URI): http://hdl.handle.net/10138/232654
Abstrakt: "Radiation-sensitive polymer gels are among the most promising three-dimensional dose verification tools developed to date. We tested the normoxic polymer gel dosimeter known by the acronym MAGIC (methacrylic and ascorbic acid in gelatin initiated by copper) to evaluate its use in boron neutron capture therapy (BNCT) dosimetry. We irradiated a large cylindrical gel phantom (diameter: 10 cm; length: 20 cm) in the epithermal neutron beam of the Finnish BNCT facility at the FiR 1 nuclear reactor. Neutron irradiation was simulated with a Monte Carlo radiation transport code MCNP. To compare dose-response, gel samples from the same production batch were also irradiated with 6 MV photons from a medical linear accelerator. Irradiated gel phantoms then underwent magnetic resonance imaging to determine their R2 relaxation rate maps. The measured and normalized dose distribution in the epithermal neutron beam was compared with the dose distribution calculated by computer simulation. The results support the feasibility of using MAGIC gel in BNCT dosimetry."
Subject: 114 Physical sciences
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